J Drugs Dermatol. 2024 Aug 1;23(8):674-679. doi: 10.36849/JDD.8471.
Acne vulgaris is a complex, multifactorial, inflammatory skin condition. Although frequently presented at dermatology clinics, the literature on adult acne is scarce, particularly concerning skin barrier function and management. We aimed to provide insights into the role of skin barrier integrity in adult acne patients and the role of cleansers and moisturizers as adjunctive to treating and maintaining adult acne. Methods: A panel of eight dermatologists who treat adult patients with acne developed a consensus paper on the role of skin barrier function and skin care in adult acne management. The modified Delphi method comprised a face-to-face meeting and online follow-up to discuss the results of a scoping literature review. Drawing from their experience and opinions, they agreed on seven consensus statements. Results: Epidermal barrier dysfunction plays a vital role in acne pathogenesis and asymmetrically impacts adult female acne. Erythema, pruritus, peeling, and xerosis are common adverse effects of first-line acne treatment options and, if not appropriately counseled and managed, can exacerbate, leading to regimen nonadherence and poor patient experience and outcomes.
Improving patient knowledge of comprehensive acne treatments, including quality adjunctive cleansers and moisturizers, may maximize regimen efficacy and provide patients with personalized and successful acne treatment and maintenance tools. J Drugs Dermatol. 2024;23(8):674-679. doi:10.36849/JDD.8471.
寻常痤疮是一种复杂的、多因素的炎症性皮肤病。尽管经常在皮肤科诊所就诊,但成人痤疮的文献很少,特别是关于皮肤屏障功能和管理的文献。我们旨在深入了解皮肤屏障完整性在成人痤疮患者中的作用,以及清洁剂和保湿剂在治疗和维持成人痤疮中的辅助作用。
方法:一组治疗成人痤疮的皮肤科医生制定了一份共识文件,内容涉及皮肤屏障功能和皮肤护理在成人痤疮管理中的作用。修改后的德尔菲法包括面对面会议和在线后续讨论,以讨论文献综述的结果。他们根据自己的经验和意见,就 7 项共识声明达成一致。
结果:表皮屏障功能障碍在痤疮发病机制中起着至关重要的作用,并对成年女性痤疮产生不对称影响。红斑、瘙痒、脱皮和干燥是一线痤疮治疗方案的常见不良反应,如果没有适当的咨询和管理,这些不良反应可能会加重,导致治疗方案不依从,患者体验和结果不佳。
结论:提高患者对全面痤疮治疗的认识,包括优质的辅助清洁剂和保湿剂,可能最大限度地提高治疗方案的疗效,并为患者提供个性化和成功的痤疮治疗和维持工具。J 皮肤病药物杂志。2024;23(8):674-679。
doi:10.36849/JDD.8471。