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Postvasectomy Semen Analysis Compliance With Utilization of a Mail-In Semen Analysis Kit.

机构信息

Department of Urology, Brigham & Women's Hospital, Boston, Massachusetts.

Department of Urology, University of California, Los Angeles Medical Center, Los Angeles, California.

出版信息

J Urol. 2024 Dec;212(6):899-906. doi: 10.1097/JU.0000000000004185. Epub 2024 Aug 2.

Abstract

PURPOSE

The AUA recommends postvasectomy semen analysis (PVSA) to verify successful vasectomy. However there remains poor patient compliance. We sought to assess whether mail-in PVSA improves patient compliance across a wide range of practice types.

MATERIALS AND METHODS

Prospective data were collected on all men who received a Fellow PVSA kit between April 2021 and August 2023 in a nationwide cohort. Date of kit activation, practice type, clinic zip code, and date of kit accession/processing at the lab were collected. Compliance rates for each practice area were reported. χ tests of independence, logistic regression models, and multivariable logistic analysis were performed to assess the impact of relevant variables.

RESULTS

Overall compliance across all practice areas was 69% following an 18-week period of observation (n = 16,105) and 82% (n = 6687) following a 40-week period. Compliance rates were highest and similar for small urology practices (<5 providers), including Veterans Affairs practices, ranging from 76% to 82% at 18 weeks to 85% to 87% at 40 weeks. Large urology practices had slightly lower compliance rates with 66% at 18 weeks to 80% at 40 weeks. The univariable logistic regression model demonstrated that patients in small urology practices have a 63% greater odds of 26-week compliance, on average, compared to those who receive care in large urology practices (odds ratio 1.63, 95% CI 1.48-1.79).

CONCLUSIONS

Fellow's mail-in PVSA offers improved PVSA compliance over previously published data. Improved compliance is seen across all practice types. Despite these successes, there is significant room for improvement to achieve 100% compliance.

摘要

目的

AUA 建议进行输精管结扎术后精液分析(PVSA)以验证输精管结扎术的成功。然而,患者的依从性仍然很差。我们试图评估邮购 PVSA 是否可以提高各种实践类型的患者依从性。

材料与方法

在全国范围内的队列研究中,前瞻性地收集了 2021 年 4 月至 2023 年 8 月期间所有接受 Fellow PVSA 试剂盒的男性的数据。收集了试剂盒激活日期、实践类型、诊所邮政编码以及实验室收到/处理试剂盒的日期。报告了每个实践领域的依从率。使用卡方检验、逻辑回归模型和多变量逻辑分析评估了相关变量的影响。

结果

在 18 周的观察期内(n=16105),所有实践领域的总体依从率为 69%,在 40 周的观察期内(n=6687),依从率为 82%。小泌尿科实践(<5 名提供者),包括退伍军人事务实践,18 周时的依从率最高且相似,为 76%至 82%,40 周时为 85%至 87%。大泌尿科实践的依从率略低,18 周时为 66%,40 周时为 80%。单变量逻辑回归模型表明,与在大型泌尿科实践中接受治疗的患者相比,小泌尿科实践中的患者平均有 63%的可能性在 26 周时具有更高的依从性(优势比 1.63,95%置信区间 1.48-1.79)。

结论

Fellow 的邮购 PVSA 提供了比之前发表的数据更高的 PVSA 依从性。所有实践类型都显示出更高的依从性。尽管取得了这些成功,但仍有很大的改进空间,以实现 100%的依从性。

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