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[患有各种ABO血型系统的化脓性和败血性感染患者机体自然抵抗力的非特异性体液因子状态]

[State of the nonspecific humoral factors of the body's natural resistance in patients with suppurative and septic infections having various ABO system blood groups].

作者信息

Romanov V A, Malafeeva E V, Belokurov Iu N, Gramenitskii A B

出版信息

Zh Mikrobiol Epidemiol Immunobiol. 1979 Dec(12):87-90.

PMID:390943
Abstract

The results of surveying 140 patients with severe purulent and septic infections of staphylococcal etiology, when compared with the distribution of the blood groups (as classified according to the ABO system) in 180 healthy donors, revealed that generalized purulent infections occurred most frequently in patients with blood groups A (II) and AB (IV), and more seldom in patients with blood groups O (I) and B (III). The average content of lysozyme, complement and normal antibodies to E. coli, as well as the average level of general bactericidal activity in the blood sera of the patients were considerably lower than in the blood sera of healthy donors; at the same time content of lysozyme, complement and normal antibodies in the blood sera of patients having different groups of blood did not reflect the degree of their predisposition or resistance to staphylococcal infections. The general bactericidal activity of the blood serum was found to correlate with the degree of predisposition or resistance to purulent septic infections of staphylococcal etiology to a greater extent than other characteristics.

摘要

对140例葡萄球菌引起的严重化脓性和败血性感染患者进行调查,并与180名健康献血者的血型分布(按照ABO系统分类)相比较,结果显示,全身性化脓性感染在A型(II)和AB型(IV)血的患者中最为常见,而在O型(I)和B型(III)血的患者中较少见。患者血清中溶菌酶、补体和抗大肠杆菌正常抗体的平均含量,以及总体杀菌活性的平均水平,均显著低于健康献血者的血清;同时,不同血型患者血清中溶菌酶、补体和正常抗体的含量,并未反映出他们对葡萄球菌感染的易感性或抵抗力程度。研究发现,血清的总体杀菌活性与对葡萄球菌引起的化脓性败血性感染的易感性或抵抗力程度的相关性,比其他特征更大。

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Zh Mikrobiol Epidemiol Immunobiol. 1979 Dec(12):87-90.
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