Shilov A B, Romanov V A, Malafeeva E V
Zh Mikrobiol Epidemiol Immunobiol. 1982 Apr(4):74-7.
Pathogenic staphylococci were found to persist in the focus of dormant infection in guinea pigs till day 100 of the experiment without changing their biological properties and sensitivity to antibiotics. The latent period of dormant staphylococcal infection was characterized by the increasing titers of antibodies to staphylococcal autostrains, by the positive results of the intradermal allergic test and the macrophage migration inhibition test with hemolytic staphylococcal allergen, as well as by the suppression of serum lysozyme activity. No changes in the content of complement and the total bactericidal activity of blood serum were detected.
发现在豚鼠潜伏感染病灶中,致病性葡萄球菌一直持续存在至实验第100天,其生物学特性及对抗生素的敏感性均未改变。潜伏性葡萄球菌感染的潜伏期表现为针对葡萄球菌自身菌株的抗体滴度升高、皮内过敏试验及用溶血性葡萄球菌变应原进行的巨噬细胞移动抑制试验结果呈阳性,以及血清溶菌酶活性受到抑制。未检测到补体含量及血清总杀菌活性的变化。