甲状腺乳头状癌咽后及咽旁淋巴结转移的研究进展。
Review of retropharyngeal and parapharyngeal nodal metastasis of papillary thyroid carcinoma.
机构信息
Wright State University, Boonshoft School of Medicine, Dayton, OH, USA.
Department of General Surgery, Wright State University, Boonshoft School of Medicine, Dayton, OH, USA.
出版信息
Am J Otolaryngol. 2024 Sep-Oct;45(5):104438. doi: 10.1016/j.amjoto.2024.104438. Epub 2024 Jul 24.
BACKGROUND
Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. In rare instances, PTC has metastasized to the retropharyngeal and parapharyngeal nodes. This is hypothesized to occur due to an aberrant lymphatic channel or via retrograde lymphatic flow following previous neck dissection.
METHODS
A literature search was conducted with keywords "parapharyngeal," "retropharyngeal," and "papillary thyroid carcinoma."
RESULTS
46 articles were identified for a total of 135 cases. The most common presenting symptom was lymphadenopathy followed by pharyngeal mass and dyspnea. 38.03 % of patients were asymptomatic. Of cases including initial treatment history, 94.44 % had a history of neck dissection. The transcervical approach was the most utilized to resect the tumors, although in recent years trans-oral robotic surgery (TORS) has also been used.
CONCLUSION
PTC metastatic to the retropharyngeal and parapharyngeal nodes is a rare occurrence that can be difficult to diagnose due its indolent nature.
背景
甲状腺乳头状癌（PTC）是最常见的甲状腺癌类型。在极少数情况下，PTC 会转移到咽后和咽旁淋巴结。这被假设是由于异常的淋巴通道，或由于先前的颈部清扫术导致逆行淋巴流动。
方法
使用关键词“咽旁”、“咽后”和“甲状腺乳头状癌”进行文献检索。
结果
共确定了 46 篇文章，共计 135 例。最常见的表现症状是淋巴结病，其次是咽部肿块和呼吸困难。38.03%的患者无症状。在包括初始治疗史的病例中，94.44%有颈部清扫术史。经颈入路是切除肿瘤最常用的方法，尽管近年来也使用了经口机器人手术（TORS）。
结论
PTC 转移到咽后和咽旁淋巴结是一种罕见的情况，由于其惰性特征，可能难以诊断。
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