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首例在美国本土的犬血管圆线虫病例。

First autochthonous case of Angiostrongylus vasorum in a domestic dog in the United States.

机构信息

1Department of Veterinary Microbiology and Pathology, Washington Animal Disease Diagnostic Laboratory, College of Veterinary Medicine, Washington State University, Pullman, WA.

2Washington State Department of Agriculture, Olympia, WA.

出版信息

J Am Vet Med Assoc. 2024 Aug 2;262(10):1-3. doi: 10.2460/javma.24.06.0408. Print 2024 Oct 1.

Abstract

OBJECTIVE

To describe the clinical presentation, diagnostic findings, and medical management of the first suspected autochthonous case of a dog in the US diagnosed with Angiostrongylus vasorum, the French heartworm.

ANIMAL

A 10-month-old Goldendoodle born in Oregon and residing in Washington State.

CLINICAL PRESENTATION, PROGRESSION, AND PROCEDURES: The dog presented for evaluation of intermittent vomiting and diarrhea. Bloodwork revealed leukocytosis with mild lymphocytosis, monocytosis, eosinophilia, and basophilia. Larvae were detected on a fecal flotation, and fecal PCR confirmed A vasorum.

TREATMENT AND OUTCOME

Administration of milbemycin oxime PO once a week for 4 weeks was initiated with recommendation to continue monthly treatment at label dose. The patient improved over the course of treatment.

CLINICAL RELEVANCE

This case highlights the clinical and diagnostic findings and medical management of A vasorum, also known as the French heartworm, in a dog in the US. Few cases of A vasorum have been reported in wild foxes in North America, mostly in eastern Canada and 1 within the eastern US. Here we report for the first time an autochthonous case of A vasorum in a domestic dog in the US and the first report of any canid in the western US. This case highlights the importance of considering A vasorum as a differential for respiratory disease, gastrointestinal disease, or inexplicable eosinophilia in canine veterinary patients in the US and raises awareness for veterinary practitioners to incorporate appropriate preventative and diagnostic measures for their canine patients.

摘要

目的

描述首例在美国被诊断患有血管圆线虫(法国心丝虫)的犬的临床症状、诊断结果和医疗管理。

动物

一只 10 个月大的出生于俄勒冈州、现居华盛顿州的金贵犬。

临床症状、进展和程序:该犬因间歇性呕吐和腹泻就诊。血液检查显示白细胞增多,伴有轻度淋巴细胞增多、单核细胞增多、嗜酸性粒细胞增多和嗜碱性粒细胞增多。粪便漂浮法检测到幼虫,粪便 PCR 证实存在血管圆线虫。

治疗和结果

给予米尔贝肟 PO 每周一次,连用 4 周,并建议按标签剂量每月继续治疗。该患者在治疗过程中逐渐好转。

临床相关性

本病例强调了美国犬血管圆线虫(也称为法国心丝虫)的临床和诊断结果以及医疗管理。在北美的野生狐狸中已报告了少数血管圆线虫病例,主要在加拿大东部和美国东部 1 例。在此,我们首次报告了美国本土犬的血管圆线虫感染病例,也是美国西部首例犬类感染病例。本病例强调了在美国,兽医临床医生在考虑犬的呼吸疾病、胃肠道疾病或不明原因的嗜酸性粒细胞增多时,应将血管圆线虫作为鉴别诊断的重要性,并提高兽医临床医生对其犬类患者采取适当预防和诊断措施的意识。

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