Department of Pedodontics & Preventive Dentistry, Sardar Patel Post Graduate Institute of Dental & Medical Sciences, Lucknow, Uttar Pradesh, India.
Annagiri Surgical and Dental Clinic, Tezpur, Assam, India.
Drug Res (Stuttg). 2024 Oct;74(8):415-420. doi: 10.1055/a-2368-4336. Epub 2024 Aug 2.
Mouthwashes, as a form of antimicrobial delivery system, rank among the safest and most effective vehicles, particularly in the case of young children. This is attributed to their ability to distribute therapeutic components across all accessible oral surfaces, including interproximal areas.
To evaluate the antibacterial efficacy of recently introduced Ayurvedic (Hiora) and triclosan-based mouthwashes among children.
A total of 45 healthy children aged 10-15 years were randomly assigned to three groups: Herbal mouthwash (Hiora), triclosan-based mouthwash (Kidodent), and normal saline as the control group. Saliva samples were collected pre-rinse, 2 minutes, 30 minutes, and 60 minutes post-rinsing with the study mouthwashes. These samples were then inoculated onto Petri dishes containing blood agar culture media, followed by incubation under both aerobic and anaerobic conditions at 37°C for 48 hours. The resulting bacterial colonies of and were counted (CFU/ml x 105). Statistical analysis, including ANOVA, Newman Keul's Post-hoc test, and a two-tailed 't' test, was conducted to determine the significance of the results.
The Ayurvedic Hiora mouthwash demonstrated the most substantial reduction in salivary bacterial colony counts of . and with statistically significant results (p<0.01).
The Ayurvedic Hiora mouthwash exhibited the highest antibacterial effectiveness, followed by the triclosan-based mouthwash in decreasing order, with saline showing the least efficacy.
漱口水作为一种抗菌药物输送系统，是最安全和最有效的载体之一，尤其是在儿童中。这是因为它们能够将治疗成分分布到所有可到达的口腔表面，包括邻面区域。
评估最近推出的基于阿育吠陀（Hiora）和三氯生的漱口水在儿童中的抗菌功效。
将 45 名年龄在 10-15 岁的健康儿童随机分为三组：草药漱口水（Hiora）、基于三氯生的漱口水（Kidodent）和生理盐水作为对照组。在使用研究漱口水漱口前、漱口后 2 分钟、30 分钟和 60 分钟收集唾液样本。然后将这些样本接种到含有血琼脂培养基的培养皿中，在 37°C 下有氧和无氧条件下孵育 48 小时。然后对 和 的细菌菌落进行计数（CFU/ml x 105）。采用方差分析（ANOVA）、Newman Keul's 事后检验和双尾 't' 检验进行统计分析，以确定结果的显著性。
阿育吠陀 Hiora 漱口水在减少唾液细菌菌落计数方面表现出最显著的效果， 和 的结果具有统计学意义（p<0.01）。
阿育吠陀 Hiora 漱口水表现出最高的抗菌效果，其次是基于三氯生的漱口水，生理盐水的效果最差。
