Department of Pedodontics and Preventive Dentistry, AME's Dental College and Hospital, Raichur, Karnataka, India.
Department of Pharmaceutics, V. L. College of Pharmacy, Raichur, Karnataka, India.
J Indian Soc Pedod Prev Dent. 2021 Jul-Sep;39(3):291-298. doi: 10.4103/jisppd.jisppd_536_20.
To compare the antibacterial efficacy of Kidodent, Probiotics, and Carica papaya Leaf extract mouthwashes in reducing Streptococcus mutans count in 8-12 years' old school children.
Sixty children of age group of 8-12 years were nominated and grouped as Group A (Kidodent mouthwash), Group B (probiotics mouthwash) Group C (C. papaya leaf extract mouthwash), and Group D (distilled water placebo). Probiotics sachets (Prebact) of about 1 g were diluted in 10 ml of water and given as mouthwash. C. papaya leaf extract was obtained by Soxhlet extraction using ethanol as a solvent. Participants were asked to rinse with mouthwashes for 30 s once daily for up to 15 days. Saliva samples were collected and inoculated using Salivarius Mitis and Agar Agar Type I at 38°C for 24 h and incubated, later colony-forming units per milliliter were determined by serial dilution and calculated using colony counter manually. Statistical Analysis: Data were statistically analyzed using the one-way ANOVA and t-test using the SPSS V.20 software.
Probiotics and C. papaya leaf extract mouthwashes were equally effective as Kidodent in reducing S. mutans count in saliva.
Probiotics and C. papaya leaf extract mouthwashes manifested potential efficacy in reduction of S. mutans.
比较儿童护牙剂、益生菌和木瓜叶提取物漱口水在减少 8-12 岁儿童口腔内变形链球菌数量方面的抗菌效果。
选择 60 名年龄在 8-12 岁的儿童，并将其分为 A 组（儿童护牙剂漱口水）、B 组（益生菌漱口水）、C 组（木瓜叶提取物漱口水）和 D 组（蒸馏水安慰剂）。益生菌小袋（Prebact）约 1 g 用 10 ml 水稀释后作为漱口水使用。用索氏提取法用乙醇作为溶剂提取木瓜叶中的提取物。参与者被要求每天用漱口水漱口 30 秒，持续 15 天。收集唾液样本并接种于 Salivarius Mitis 和琼脂 I 型，在 38°C 下孵育 24 小时，然后通过连续稀释并用手动菌落计数器计算每毫升的菌落形成单位。统计分析：使用 SPSS V.20 软件对数据进行单因素方差分析和 t 检验进行统计学分析。
益生菌和木瓜叶提取物漱口水在减少唾液中变形链球菌数量方面与儿童护牙剂同样有效。
益生菌和木瓜叶提取物漱口水在减少变形链球菌方面表现出潜在的功效。
