Lancet Public Health. 2024 Aug;9(8):e539-e550. doi: 10.1016/S2468-2667(24)00122-1.
Fall-related mortality has increased rapidly over the past two decades in the USA, but the extent to which mortality varies across racial and ethnic populations, counties, and age groups is not well understood. The aim of this study was to estimate age-standardised mortality rates due to falls by racial and ethnic population, county, and age group over a 20-year period.
Redistribution methods for insufficient cause of death codes and validated small-area estimation methods were applied to death registration data from the US National Vital Statistics System and population data from the US National Center for Health Statistics to estimate annual fall-related mortality. Estimates from 2000 to 2019 were stratified by county (n=3110) and five mutually exclusive racial and ethnic populations: American Indian or Alaska Native (AIAN), Asian or Pacific Islander (Asian), Black, Latino or Hispanic (Latino), and White. Estimates were corrected for misreporting of race and ethnicity on death certificates using published misclassification ratios. We masked (ie, did not display) estimates for county and racial and ethnic population combinations with a mean annual population of less than 1000. Age-standardised mortality is presented for all ages combined and for age groups 20-64 years (younger adults) and 65 years and older (older adults).
Nationally, in 2019, the overall age-standardised fall-related mortality rate for the total population was 13·4 deaths per 100 000 population (95% uncertainty interval 13·3-13·6), an increase of 65·3% (61·9-68·8) from 8·1 deaths per 100 000 (8·0-8·3) in 2000, with the largest increases observed in older adults. Fall-related mortality at the national level was highest across all years in the AIAN population (in 2019, 15·9 deaths per 100 000 population [95% uncertainty interval 14·0-18·2]) and White population (14·8 deaths per 100 000 [14·6-15·0]), and was about half as high among the Latino (8·7 deaths per 100 000 [8·3-9·0]), Black (8·1 deaths per 100 000 [7·9-8·4]), and Asian (7·5 deaths per 100 000 [7·1-7·9]) populations. The disparities between racial and ethnic populations varied widely by age group, with mortality among younger adults highest for the AIAN population and mortality among older adults highest for the White population. The national-level patterns were observed broadly at the county level, although there was considerable spatial variation across ages and racial and ethnic populations. For younger adults, among almost all counties with unmasked estimates, there was higher mortality in the AIAN population than in all other racial and ethnic populations, while there were pockets of high mortality in the Latino population, particularly in the Mountain West region. For older adults, mortality was particularly high in the White population within clusters of counties across states including Florida, Minnesota, and Wisconsin.
Age-standardised mortality due to falls increased over the study period for each racial and ethnic population and almost every county. Wide variation in mortality across geography, age, and race and ethnicity highlights areas and populations that might benefit most from efficacious fall prevention interventions as well as additional prevention research.
US National Institutes of Health (Intramural Research Program, National Institute on Minority Health and Health Disparities; National Heart, Lung, and Blood Institute; Intramural Research Program, National Cancer Institute; National Institute on Aging; National Institute of Arthritis and Musculoskeletal and Skin Diseases; Office of Disease Prevention; and Office of Behavioral and Social Sciences Research).
在过去的二十年中,美国与跌倒相关的死亡率迅速上升,但不同种族和族裔人群、县和年龄组的死亡率差异程度尚不清楚。本研究的目的是估计 20 年来因跌倒导致的标准化死亡率,按种族和族裔人口、县和年龄组进行分层。
利用美国国家生命统计系统的死亡登记数据和美国国家卫生统计中心的人口数据,应用不足死因编码再分配方法和经过验证的小区域估计方法,估计每年与跌倒相关的死亡率。2000 年至 2019 年的死亡率按县(n=3110)和五个相互排斥的种族和族裔群体进行分层:美洲印第安人或阿拉斯加原住民(AIAN)、亚洲或太平洋岛民(亚裔)、黑种人、拉丁裔或西班牙裔(拉丁裔)和白种人。利用已发表的错分率校正死亡证明上种族和族裔报告错误的问题。我们对县和种族和族裔人群组合的估计值进行了屏蔽(即,未显示),这些组合的平均年人口少于 1000。所有年龄组和 20-64 岁(年轻成年人)和 65 岁及以上(老年人)年龄组的年龄标准化死亡率均有呈现。
在全国范围内,2019 年,总人口因跌倒导致的标准化死亡率为每 10 万人中有 13.4 人死亡(95%不确定区间 13.3-13.6),比 2000 年每 10 万人中有 8.1 人死亡(8.0-8.3)增加了 65.3%(61.9-68.8),其中老年人的增幅最大。全国范围内,AIAN 人口(2019 年每 10 万人中有 15.9 人死亡[95%不确定区间 14.0-18.2])和白人人口(每 10 万人中有 14.8 人死亡[14.6-15.0])的跌倒相关死亡率在所有年份均最高,而拉丁裔(每 10 万人中有 8.7 人死亡[8.3-9.0])、黑种人(每 10 万人中有 8.1 人死亡[7.9-8.4])和亚裔(每 10 万人中有 7.5 人死亡[7.1-7.9])的死亡率则相对较低。种族和族裔人群之间的差异在很大程度上因年龄组而异,年轻成年人中 AIAN 人口的死亡率最高,老年人中白人人口的死亡率最高。在县一级也广泛观察到全国性模式,尽管在年龄和种族和族裔人群方面存在相当大的空间差异。对于年轻成年人,在几乎所有未屏蔽估计的县中,AIAN 人口的死亡率都高于其他所有种族和族裔人口,而在拉丁裔人口中则存在一些死亡率较高的地区,特别是在西部山区。对于老年人,在包括佛罗里达州、明尼苏达州和威斯康星州在内的多个州的县集群中,白人人口的死亡率尤其高。
在研究期间,每个种族和族裔人口以及几乎每个县的跌倒导致的标准化死亡率都有所增加。死亡率在地理、年龄和种族和族裔方面的广泛差异突出了可能从有效预防跌倒干预措施以及更多预防研究中受益的地区和人群。
美国国立卫生研究院(内部研究计划,少数民族健康和健康差异国家研究所;国家心肺血液研究所;内部研究计划,国家癌症研究所;国家老龄化研究所;国家关节炎和肌肉骨骼及皮肤病研究所;疾病预防办公室;和行为与社会科学研究办公室)。