膀胱内注入乙磺半胱氨酸（Epodyl）治疗非浸润性膀胱癌（Ta期）。

Intravesical ethoglucid (Epodyl) for treatment of noninvasive bladder cancer (stage Ta).

作者信息

Larson A, Fritjofsson A

出版信息

Ups J Med Sci. 1985;90(2):127-32. doi: 10.3109/03009738509178649.

Abstract

Widespread, well differentiated (grade I) bladder tumours confined to the mucosa (stage Ta) were treated with regular intravesical instillations of ethoglucid (Epodyl) in 24 patients. The therapeutic schedule could be followed in all but one patient, in whom side effects necessitated cessation of treatment. Complete response was obtained in 75% of the patients, and during continued prophylactic therapy 90% remained tumour-free. After termination of the treatment, however, new tumours appeared in 60-80% of the patients.

摘要

24例广泛的、高分化（I级）且局限于黏膜层（Ta期）的膀胱肿瘤患者接受了乙磺半胱氨酸（Epodyl）常规膀胱内灌注治疗。除1例患者因副作用而不得不停止治疗外，所有患者均完成了治疗方案。75%的患者获得了完全缓解，在持续的预防性治疗期间，90%的患者无肿瘤复发。然而，治疗结束后，60%-80%的患者出现了新的肿瘤。