Nielsen H V, Thybo E
Scand J Urol Nephrol. 1979;13(1):59-63. doi: 10.3109/00365597909180000.
Multiple, non-invasive bladder papillomas were treated with intravesical instillation of Epodyl in 44 patients. Irritative cystitis occurred in 16 per cent of the series, and in these cases Epodyl treatment had to be stopped. Total or partial disappearance of the papillomas was seen after 16 months of treatment in 43% of the total series. This was the minimum success rate, since all the patients who left the study were counted as failures. When the treatment could be carried through, total or partial disappearance of papillomas occurred in 19 of 29 patients (66%). Epodyl has a place in the treatment of vesical papillomas when other methods have failed.
44例多发性非侵袭性膀胱乳头状瘤患者接受了膀胱内灌注Epodyl治疗。该组患者中有16%发生了刺激性膀胱炎,在这些病例中,必须停止Epodyl治疗。在整个治疗系列中,43%的患者在治疗16个月后乳头状瘤完全或部分消失。这是最低成功率,因为所有退出研究的患者都被计为治疗失败。当治疗能够持续进行时,29例患者中有19例(66%)乳头状瘤完全或部分消失。当其他治疗方法失败时,Epodyl在膀胱乳头状瘤的治疗中占有一席之地。