使用经氯喹处理的粒细胞和血小板诊断免疫性血细胞减少症。
Use of chloroquine-treated granulocytes and platelets in the diagnosis of immune cytopenias.
作者信息
Metcalfe P, Minchinton R M, Murphy M F, Waters A H
出版信息
Vox Sang. 1985;49(5):340-5. doi: 10.1111/j.1423-0410.1985.tb00809.x.
Abstract
A chloroquine modification of the fluorescent antiglobulin technique has been used to demonstrate cell-specific antibodies in the presence of HLA antibodies. This is of particular value in the diagnosis of alloimmune neonatal thrombocytopenia and neutropenia, post-transfusion purpura, and in the investigation of febrile non-haemolytic transfusion reactions and of patients refractory to platelet transfusions.
摘要
荧光抗球蛋白技术的氯喹修饰法已用于在存在HLA抗体的情况下检测细胞特异性抗体。这在诊断同种免疫性新生儿血小板减少症和中性粒细胞减少症、输血后紫癜，以及在调查发热性非溶血性输血反应和对血小板输注难治的患者方面具有特别的价值。
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