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青年女性特发性颈髓梗死致急性颈痛和弛缓性瘫痪:病例报告。

Idiopathic cervical cord infarction in a young girl presenting with acute neck pain and flaccid paralysis: a case report.

机构信息

Trauma and Injury Research Center, Iran University of Medical Sciences, Tehran, Iran.

出版信息

Spinal Cord Ser Cases. 2024 Aug 3;10(1):55. doi: 10.1038/s41394-024-00659-w.

Abstract

INTRODUCTION

Spinal cord infarction (SCI) is a rare disease representing nearly 1% of all strokes with a wide variety of symptoms at presentation. SCI diagnosis is very challenging owing to its low incidence and the variety of symptoms, and could be misdiagnosed with neuromyelitis optica spectrum disorders (NMOSD).

CASE PRESENTATION

We describe the case of an 18-year-old girl who presented to the emergency department with acute neck pain and flaccid paralysis of the left upper and lower extremities. Few hours later, she developed apnea and was endotracheally intubated. Brain MRI was normal but spinal cord MRI revealed non-enhancing longitudinal abnormal high T2 signal intensity extending from C1 to C5. The patient underwent steroid therapy with methylprednisolone (1 g daily for 7 consecutive days) combined with physiotherapy. She was extubated after 3 weeks and discharged after 30 days of hospitalization with a muscle force of 4/5 in her left extremities.

DISCUSSION

Idiopathic SCI in adolescence is a rare but often devastating disorder with unknown pathophysiology, however, some specific conditions in adolescent such as mechanical stresses on the immature spine can be considered as risk factors for SCI development. Early diagnosis and treatment can improve outcomes in SCI.

摘要

介绍

脊髓梗死(SCI)是一种罕见疾病,约占所有中风的 1%,其表现症状多种多样。由于发病率低且症状多样,SCI 的诊断极具挑战性,容易误诊为视神经脊髓炎谱系疾病(NMOSD)。

病例介绍

我们描述了一例 18 岁女孩的病例,她因急性颈部疼痛和左侧上下肢弛缓性瘫痪到急诊科就诊。几小时后,她出现呼吸暂停并被气管插管。脑部 MRI 正常,但脊髓 MRI 显示从 C1 到 C5 的非增强性纵向异常高 T2 信号强度。患者接受了甲泼尼龙(1 g/d,连续 7 天)联合物理疗法的类固醇治疗。3 周后患者拔管,30 天后出院,左侧肢体肌力为 4/5。

讨论

青少年特发性 SCI 是一种罕见但常具破坏性的疾病,其发病机制不明,但青少年的一些特定情况,如不成熟脊柱上的机械应力,可被视为 SCI 发展的危险因素。早期诊断和治疗可以改善 SCI 的预后。

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