Cascaldi Bruna Grici, Cardoso Filho Antero Pinto, Arruda Gustavo Viani, Rocha Eduardo Melani, Paula Jayter Silva
Department of Ophthalmology, Otorhinolaryngology and Head & Neck Surgery at Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
Department of Medical Images, Hematology and Oncology at Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
Ocul Surf. 2024 Oct;34:183-193. doi: 10.1016/j.jtos.2024.07.011. Epub 2024 Aug 5.
Meibomian gland (MG) dysfunction and glaucoma are very prevalent ocular conditions that significantly impact patients' quality of life. A growing number of clinical and experimental studies have reported an association between the use of topical eye drops to reduce intraocular pressure and the development or exacerbation of MG dysfunction. Studies investigating the impact of glaucoma eyedrops on MG diagnostic parameters have shown variable results, particularly regarding the morphology and function of MG and tear film instability. Herein, we corroborated the findings of greater changes in morphological and functional variables related to MG in patients treated with antiglaucoma eye drops through a systematic review and meta-analysis.
睑板腺（MG）功能障碍和青光眼是非常常见的眼部疾病，会显著影响患者的生活质量。越来越多的临床和实验研究报告称，使用局部滴眼液降低眼压与MG功能障碍的发生或加重之间存在关联。研究青光眼滴眼液对MG诊断参数影响的研究结果不一，特别是在MG的形态和功能以及泪膜稳定性方面。在此，我们通过系统评价和荟萃分析证实了使用抗青光眼滴眼液治疗的患者中与MG相关的形态和功能变量有更大变化的研究结果。
