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原发性肝鳞状细胞癌:一例报告

Primary Hepatic Squamous Cell Carcinoma: A Case Report.

作者信息

Lyagoubi Manal, Mehdaoui Chourouq, Haloui Anass, Karish Nassira, Ismaili Zahi, Bennani Amal

机构信息

Pathology, Faculty of Medicine and Pharmacy of Oujda, Mohammed 1st University, Oujda, MAR.

Pathology, Mohammed VI University Hospital, Faculty of Medicine, Mohammed 1st University, Oujda, MAR.

出版信息

Cureus. 2024 Jul 4;16(7):e63803. doi: 10.7759/cureus.63803. eCollection 2024 Jul.

DOI:10.7759/cureus.63803
PMID:39099991
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11297720/
Abstract

Primary squamous cell carcinoma (SCC) of the liver, a notably uncommon type of cancer, is frequently linked with diverse hepatic conditions including hepatic cysts, hepatolithiasis, and hepatic teratoma. Literature indicates that only approximately 30 cases of primary SCC of the liver have been documented. Herein, we report a 54-year-old previously healthy patient who was presented with cholangitis symptoms. Examinations revealed normal vitals. However, deranged liver function with transaminitis and hyperbilirubinemia were noticed. A CT scan showed a hepatic mass with bile duct dilation. Biopsy confirmed hepatic squamous cell carcinoma, leading to chemotherapy treatment. Despite treatment, the survival outcomes for this cancer remain limited, and the prognosis is generally unfavorable.

摘要

原发性肝鳞状细胞癌(SCC)是一种极为罕见的癌症类型,常与多种肝脏疾病相关,包括肝囊肿、肝内胆管结石和肝畸胎瘤。文献表明,仅有约30例原发性肝SCC的病例被记录在案。在此,我们报告一名54岁既往健康的患者,其出现了胆管炎症状。检查显示生命体征正常。然而,发现肝功能紊乱,伴有转氨酶升高和高胆红素血症。CT扫描显示肝脏有肿块伴胆管扩张。活检确诊为肝鳞状细胞癌,随后进行了化疗。尽管进行了治疗,这种癌症的生存结果仍然有限,预后通常不佳。

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本文引用的文献

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Primary squamous cell carcinoma of the liver: a case report.原发性肝鳞癌 1 例报告。
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Primary hepatic adenosquamous carcinoma: A rare case report.原发性肝性腺鳞癌:1 例罕见病例报告。
Indian J Pathol Microbiol. 2021 Jun;64(Supplement):S140-S142. doi: 10.4103/IJPM.IJPM_785_18.
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Primary Squamous Cell Carcinoma of the Liver is Rare but Hostile: Case Series and Comprehensive Review of the Literature.原发性肝鳞状细胞癌罕见但恶性程度高:病例系列及文献综述
Cancer Manag Res. 2021 Jan 29;13:829-837. doi: 10.2147/CMAR.S290523. eCollection 2021.
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Primary squamous cell carcinoma of the liver: a case report.原发性肝鳞状细胞癌:一例报告
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Primary Squamous Cell Carcinoma of Liver: Case Series and Review of Literatures.原发性肝鳞状细胞癌:病例系列及文献综述
Medicine (Baltimore). 2015 Jul;94(28):e868. doi: 10.1097/MD.0000000000000868.
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Primary squamous cell carcinoma of the liver concomitant with primary colon cancer: report of a case.肝原发性鳞状细胞癌合并原发性结肠癌:1例报告
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Programmed cell death 1 (PD-1) and its ligand (PD-L1) in common cancers and their correlation with molecular cancer type.常见癌症中的程序性细胞死亡蛋白1(PD-1)及其配体(PD-L1)及其与分子癌症类型的相关性。
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