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同种异体移植物与自体移植物重建髌股内侧韧带后临床结果的比较:一项匹配队列分析。

Comparison of Clinical Outcomes After Medial Patellofemoral Ligament Reconstruction With Allograft Versus Autograft: A Matched-Cohort Analysis.

作者信息

Henstenburg Jeffrey, Pezzulo Joshua D, Farronato Dominic M, Johnson Emma B, Bodnar John, Petrucelli Philip, Dodson Christopher, Freedman Kevin B, Cohen Steven B, Hammoud Sommer

机构信息

The Rothman Institute at Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

出版信息

Orthop J Sports Med. 2024 Jul 31;12(7):23259671241256983. doi: 10.1177/23259671241256983. eCollection 2024 Jul.

Abstract

BACKGROUND

Disruption of the medial patellofemoral ligament (MPFL) may lead to recurrent lateral patellar dislocation and patellofemoral chondral injury. Despite significant previous work investigating numerous performance parameters, the optimal graft choice for MPFL reconstruction for patellar instability remains unclear.

PURPOSE

To compare functional outcomes scores, subjective recurrent instability, and revision rates between autograft and allograft in MPFL reconstruction.

STUDY DESIGN

Cohort study; Level of evidence, 3.

METHODS

Patients who underwent MPFL reconstruction with autograft between 2013 and 2018 were identified. A 2:1 comparison group of patients who underwent MPFL reconstruction with allograft was matched by sex, age (±3 years), and body mass index (BMI) (±3 kg/m). Patient characteristics, preoperative radiograph measurements, and intraoperative data were compared between the groups, as were patient-reported outcome measures, including International Knee Documentation Committee (IKDC) score, Lysholm score, Single Assessment Numerical Evaluation (SANE), and visual analog scale (VAS) for pain. Subjective recurrent instability and revision rate were also compared between groups.

RESULTS

The autograft group was composed of 30 patients (13 male, 17 female) with a mean age of 24.4 years and mean BMI of 25.0 kg/m, and the allograft group was composed of 60 matched patients (25 male, 35 female) with a mean age of 24.1 years and mean BMI of 25.1 kg/m. The autograft and allograft groups reported similar IKDC scores (73.0 vs 73.7; = .678), Lysholm scores (77.5 vs 80.7; = .514), SANE (72.0 vs 75.8; = .236), and VAS pain (30.7 vs 26.6; = .482), as well as similar rates of postoperative patellar subluxations (20.0% vs 19.3%; = .867) and dislocations (10.0% vs 15.0%; = .805).

CONCLUSION

Both allograft and autograft were found to be viable options for MPFL reconstruction. There were no significant group differences in failure rates, patient-reported outcomes, pain, or complications between autograft and allograft MPFL reconstruction in this series.

摘要

背景

髌股内侧韧带(MPFL)断裂可能导致髌骨反复外侧脱位和髌股关节软骨损伤。尽管此前已有大量研究探讨了众多性能参数,但对于髌骨不稳定的MPFL重建而言,最佳移植物选择仍不明确。

目的

比较自体移植物和同种异体移植物在MPFL重建中的功能结局评分、主观复发性不稳定及翻修率。

研究设计

队列研究;证据等级,3级。

方法

确定2013年至2018年间接受自体移植物MPFL重建的患者。按照2:1的比例选取接受同种异体移植物MPFL重建的患者作为比较组,根据性别、年龄(±3岁)和体重指数(BMI)(±3kg/m²)进行匹配。比较两组患者的特征、术前X线测量结果和术中数据,以及患者报告的结局指标,包括国际膝关节文献委员会(IKDC)评分、Lysholm评分、单评估数值评定(SANE)和疼痛视觉模拟量表(VAS)。还比较了两组之间的主观复发性不稳定和翻修率。

结果

自体移植物组由30例患者(男13例,女17例)组成,平均年龄24.4岁,平均BMI为25.0kg/m²;同种异体移植物组由60例匹配患者(男25例,女35例)组成,平均年龄24.1岁,平均BMI为25.1kg/m²。自体移植物组和同种异体移植物组报告的IKDC评分(73.0对73.7;P = 0.678)、Lysholm评分(77.5对80.7;P = 0.514)、SANE评分(72.0对75.8;P = 0.236)和VAS疼痛评分(30.7对26.6;P = 0.482)相似,术后髌骨半脱位(20.0%对19.3%;P = 0.867)和脱位(10.0%对15.0%;P = 0.805)的发生率也相似。

结论

自体移植物和同种异体移植物均被发现是MPFL重建的可行选择。在本系列研究中,自体移植物和同种异体移植物MPFL重建在失败率、患者报告的结局、疼痛或并发症方面无显著组间差异。

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