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小儿髌股内侧韧带重建中自体移植与异体移植的比较

Autograft vs Allograft Comparison in Pediatric Medial Patellofemoral Ligament Reconstruction.

作者信息

Hendawi Tariq, Godshaw Brian, Flowers Christopher, Stephens Isabel, Haber Lawrence, Waldron Sean

机构信息

Department of Orthopedic Surgery, Ochsner Clinic Foundation, New Orleans, LA.

The University of Queensland Faculty of Medicine, Ochsner Clinical School, New Orleans, LA.

出版信息

Ochsner J. 2019 Summer;19(2):96-101. doi: 10.31486/toj.18.0081.

Abstract

Patella instability and medial patellofemoral ligament (MPFL) injury are frequently encountered in pediatric patients. MPFL reconstruction is often chosen to treat this condition with good results; however, no consensus has been reached about which graft or technique to use. The purpose of this study was to evaluate the differences in graft survivorship, clinical outcomes (assessed with Kujala scores), and cost between autograft and allograft usage in MPFL reconstruction in pediatric patients. In this retrospective review of patients who underwent MPFL reconstruction between 2012-2015, autograft gracilis tendon was used for Group 1, and allograft gracilis tendon was used for Group 2. Outcomes were graft survivorship, postoperative Kujala scores, operative time, costs, graft size, and tibial tubercle-trochlear groove distance. Fifty-six patients were included in this study, 21 in Group 1 and 35 in Group 2. No differences in age, sex, or chronicity were seen between the groups. Patients in Group 1 had longer operative times (134.5 minutes vs 97.3 minutes, 0.0002), higher rates of graft failure (28.6% vs 0%, =0.0037), and lower Kujala scores (80.3 vs 92.1, =0.0032) compared to Group 2. All graft failures occurred in patients with chronic patella dislocations and occurred an average of 13.8 months postoperatively. Overall, autograft was costlier than allograft because of the cost of reoperation. This study supports the use of allograft for chronic patellar instability because of improved graft survivorship and clinical outcome scores, as well as the lower cost and reoperation rate.

摘要

髌骨不稳定和髌股内侧韧带(MPFL)损伤在儿科患者中经常出现。MPFL重建术常被用于治疗这种疾病,且效果良好;然而,对于使用哪种移植物或技术尚未达成共识。本研究的目的是评估儿科患者MPFL重建术中使用自体移植物和同种异体移植物在移植物存活率、临床结果(用库贾拉评分评估)和成本方面的差异。在这项对2012年至2015年间接受MPFL重建术的患者的回顾性研究中,第1组使用自体股薄肌腱,第2组使用同种异体股薄肌腱。结果指标包括移植物存活率、术后库贾拉评分、手术时间、成本、移植物大小以及胫骨结节 - 滑车沟距离。本研究纳入了56例患者,第1组21例,第2组35例。两组在年龄、性别或病程方面未见差异。与第2组相比,第1组患者的手术时间更长(134.5分钟对97.3分钟,P = 0.0002),移植物失败率更高(28.6%对0%,P = 0.0037),库贾拉评分更低(80.3对92.1,P = 0.0032)。所有移植物失败均发生在慢性髌骨脱位患者中,平均发生在术后13.8个月。总体而言,由于再次手术的费用,自体移植物比同种异体移植物成本更高。本研究支持在慢性髌骨不稳定的治疗中使用同种异体移植物,因为其移植物存活率和临床结果评分更高,成本和再次手术率更低。

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