Zhong Yi, Wei Er-Ting, Wu Leran, Wang Yong, Lin Qin, Wu Nihuan, Chen Hongpeng, Tang Nan
School of Pharmacy, Guangdong Medical University, Dongguan, Guangdong 523808, P. R. China.
School of Biomedical Engineering, Guangdong Medical University, Dongguan, Guangdong 523808, P. R. China.
ACS Omega. 2024 Jul 16;9(30):32268-32286. doi: 10.1021/acsomega.4c02775. eCollection 2024 Jul 30.
Skin is the first defense barrier of the human body, which can resist the invasion of external dust, microorganisms and other pollutants, and ensure that the human body maintains the homeostasis of the internal environment. Once the skin is damaged, the health threat to the human body will increase. Wound repair and the human internal environment are a dynamic process. How to effectively accelerate the healing of wounds without affecting the internal environment of the human body and guarantee that the repaired tissue retains its original function as much as possible has become a research hotspot. With the advancement of technology, researchers have combined new technologies to develop and prepare various types of materials for wound healing. This article will introduce the wound repair materials developed and prepared in recent years from three types: nanofibers, composite hydrogels, and other new materials. The paper aims to provide reference for researchers in related fields to develop and prepare multifunctional materials. This may be helpful to design more ideal materials for clinical application, and then achieve better wound healing and regeneration effects.
皮肤是人体的第一道防御屏障，它能够抵御外部灰尘、微生物及其他污染物的入侵，并确保人体维持内环境的稳态。一旦皮肤受损，对人体的健康威胁就会增加。伤口修复与人体内部环境是一个动态过程。如何在不影响人体内部环境的情况下有效加速伤口愈合，并保证修复后的组织尽可能保留其原有功能，已成为一个研究热点。随着技术的进步，研究人员结合新技术开发并制备了各种用于伤口愈合的材料。本文将从纳米纤维、复合水凝胶和其他新材料这三种类型介绍近年来开发制备的伤口修复材料。本文旨在为相关领域的研究人员开发制备多功能材料提供参考。这可能有助于设计出更理想的临床应用材料，进而实现更好的伤口愈合和再生效果。
