Phuyal Subash, Paudel Sushanta, Chhetri Suchit Thapa, Phuyal Prakash, Shrestha Sadina, Maharjan Anzil Man Singh
Department of Neuroradiology Upendra Devkota Memorial National Institute of Neurology and Allied Sciences Kathmandu Nepal.
Nepalese Army Institute of Health Sciences Kathmandu Nepal.
Health Sci Rep. 2024 Aug 1;7(8):e2285. doi: 10.1002/hsr2.2285. eCollection 2024 Aug.
Susceptibility-weighted imaging (SWI) can help in the diagnosis of thrombus within the vessel in acute ischemic stroke, known as susceptibility vessel sign (SVS), and detection of SVS within the vessel can predict treatment modality and outcome. In this study, the purpose is to correlate the SVS on SWI with different parameters of stroke.
This prospective cross-sectional study enrolled consecutive stroke patients with vessel occlusion on magnetic resonance angiography (MRA) over 1 year. The relationship between SVS on SWI with risk factors, territory involved, and length of thrombus was correlated with the National Institutes of Health Stroke Scale (NIHSS).
A total of 105 patients were enrolled in this study. Sixty-two percent (66 out of 105) of patients showed SVS on SWI with MRA-positive occlusion. A positive correlation was observed between SVS on SWI and the risk factor ( = 0.003, chi-square test), with 86% of patients with heart disease and 47% with hypertension exhibiting SVS. Additionally, a positive correlation was observed between SVS on SWI and territorial occlusion ( = 0.000, chi-square test). A moderate positive correlation was observed between the NIHSS and thrombus length ( = 0.002, Pearson's correlation coefficient), with a Pearson's coefficient of 0.367.
SWI can be useful in identifying the location of the thrombus, and NIHSS can determine the thrombus length in acute stroke. A higher incidence of SVS can be associated with risk factors, and it also depends upon the site of occlusion of the vessel.
磁敏感加权成像（SWI）有助于急性缺血性卒中血管内血栓的诊断，即磁敏感血管征（SVS），血管内SVS的检测可预测治疗方式和预后。本研究旨在将SWI上的SVS与卒中的不同参数进行关联。
这项前瞻性横断面研究纳入了连续1年以上磁共振血管造影（MRA）显示血管闭塞的卒中患者。将SWI上的SVS与危险因素、受累区域和血栓长度之间的关系与美国国立卫生研究院卒中量表（NIHSS）进行关联。
本研究共纳入105例患者。62%（105例中的66例）的患者在SWI上显示SVS且MRA阳性闭塞。SWI上的SVS与危险因素之间存在正相关（P = 0.003，卡方检验），86%的心脏病患者和47%的高血压患者表现出SVS。此外，SWI上的SVS与区域闭塞之间存在正相关（P = 0.000，卡方检验）。NIHSS与血栓长度之间存在中度正相关（P = 0.002，Pearson相关系数），Pearson系数为0.367。
SWI有助于识别血栓位置，NIHSS可确定急性卒中的血栓长度。SVS的较高发生率可能与危险因素有关，也取决于血管闭塞部位。
