Medical College of Soochow University, Suzhou, 215123, China.
Department of Neurology, Tongzhou People's Hospital, Nantong, 226300, China.
Sci Rep. 2021 Mar 11;11(1):5641. doi: 10.1038/s41598-021-84269-8.
The prominent vessel sign (PVS) on susceptibility-weighted imaging (SWI) is not displayed in all cases of acute ischemia. We aimed to investigate the factors associated with the presence of PVS in stroke patients. Consecutive ischemic stroke patients admitted within 24 h from symptom onset underwent emergency multimodal MRI at admission. Associated factors for the presence of PVS were analyzed using univariate analyses and multivariable logistic regression analyses. A total of 218 patients were enrolled. The occurrence rate of PVS was 55.5%. Univariate analyses showed significant differences between PVS-positive group and PVS-negative group in age, history of coronary heart disease, baseline NIHSS scores, total cholesterol, hemoglobin, anterior circulation infarct, large vessel occlusion, and cardioembolism. Multivariable logistic regression analyses revealed that the independent factors associated with PVS were anterior circulation infarct (odds ratio [OR] 13.7; 95% confidence interval [CI] 3.5-53.3), large vessel occlusion (OR 123.3; 95% CI 33.7-451.5), and cardioembolism (OR 5.6; 95% CI 2.1-15.3). Anterior circulation infarct, large vessel occlusion, and cardioembolism are independently associated with the presence of PVS on SWI.
在磁敏感加权成像（SWI）上，并非所有急性缺血患者都显示明显血管征（PVS）。本研究旨在探讨与脑卒中患者 PVS 存在相关的因素。发病 24 小时内的连续缺血性脑卒中患者在入院时接受了紧急多模态 MRI 检查。采用单因素分析和多因素逻辑回归分析来分析 PVS 存在的相关因素。共纳入 218 例患者。PVS 阳性率为 55.5%。单因素分析显示，PVS 阳性组与 PVS 阴性组在年龄、冠心病史、基线 NIHSS 评分、总胆固醇、血红蛋白、前循环梗死、大血管闭塞和心源性栓塞等方面存在显著差异。多因素逻辑回归分析显示，与 PVS 相关的独立因素为前循环梗死（OR 13.7；95%CI 3.5-53.3）、大血管闭塞（OR 123.3；95%CI 33.7-451.5）和心源性栓塞（OR 5.6；95%CI 2.1-15.3）。前循环梗死、大血管闭塞和心源性栓塞与 SWI 上 PVS 的存在独立相关。
