Alene Dessie, Maru Moges, Demessie Yitayew, Mulaw Asnakew
Department of Pathobiology, College of Veterinary Medicine and Animal Science University of Gondar, Gondor, Ethiopia.
Department of Biomedical, College of Veterinary Medicine and Animal Science University of Gondar, Gondor, Ethiopia.
Front Vet Sci. 2024 Jul 19;11:1411272. doi: 10.3389/fvets.2024.1411272. eCollection 2024.
Zoonotic metacestodes present a significant threat to both veterinary and public health. Specifically, the prevalence of metacestodes is often concentrated among consumers of raw meat and underdeveloped countries. The objective of this study was to estimate the prevalence of condemned red offal and examine the gross and histopathology features of zoonotic metacestodes. A cross-sectional study was conducted from November 2022 to July 2023 at the Bahir Dar municipal abattoir. A simple random sampling method employed in the abattoir survey to investigate pathological changes of offal and its rate of condemnation. Following a gross inspection of the red offal, representative tissue samples collected and preserved in 10% neutral buffered formalin. Subsequently, the size and number of cysts determined, and their viability and fertility evaluated. Hematoxylin and eosin staining utilized to analyze various lesions with microscope. A total of 340 cattle examined and 7.5% red offal condemned due to hydatid cysts 4.12% in the lungs, 3% in the liver, 0.6% in the kidneys, and 0.9% in other organs. Red offal condemned due to 0.6% in the liver and 0.3% in the tongue. A statistically significance relationship was found between lung rejection due to hydatidosis ( < 0.05), body condition score, and origin of the animal. Among the detected calcified cysts, 83.34% of and 47.62% of hydatid cysts. Histopathological examination revealed hydatid cysts and their oncospheres within the portal circulation, as well as necrotized, calcified daughter cysts observed on Bowman's capsule. The alveoli and bronchiole parenchyma compressed with pressure of protoscolices and it infiltrated by eosinophils. The cyst wall is attached to the thick hepatic capsule of the liver, with the hepatic parenchyma displaying islands of irregular hepatocytes. detected in the deteriorated and necrotized muscle bundles, along with granulomatous lesions characterized by infiltration of mononuclear cells. Gross and histological examinations is invaluable tool for diagnosing hydatidosis and cysticercosis, providing well-organized baseline data to enhance our understanding the burden of zoonotic metacestodes.
人畜共患的中绦期幼虫对兽医和公共卫生都构成了重大威胁。具体而言，中绦期幼虫的流行往往集中在生肉消费者和不发达国家中。本研究的目的是估计被拒收的红色内脏器官的患病率，并检查人畜共患中绦期幼虫的大体和组织病理学特征。2022年11月至2023年7月在巴赫达尔市屠宰场进行了一项横断面研究。在屠宰场调查中采用简单随机抽样方法，以调查内脏器官的病理变化及其拒收率。在对红色内脏器官进行大体检查后，采集代表性组织样本并保存在10%中性缓冲福尔马林中。随后，确定囊肿的大小和数量，并评估其活力和繁殖力。利用苏木精和伊红染色在显微镜下分析各种病变。总共检查了340头牛，7.5%的红色内脏器官因包虫囊肿而被拒收，其中肺部占4.12%，肝脏占3%，肾脏占0.6%，其他器官占0.9%。因肝脏病变导致红色内脏器官被拒收的占0.6%，舌头病变导致的占0.3%。发现因包虫病导致的肺部拒收（<0.05）、身体状况评分和动物来源之间存在统计学显著关系。在检测到的钙化囊肿中，83.34%的[此处原文缺失相关信息]和47.62%的包虫囊肿。组织病理学检查显示门静脉循环内有包虫囊肿及其六钩蚴，以及在鲍曼囊上观察到的坏死、钙化的子囊肿。肺泡和细支气管实质被原头节压迫并被嗜酸性粒细胞浸润。囊肿壁附着在肝脏厚厚的肝包膜上，肝实质显示出不规则肝细胞岛。在退化和坏死的肌束中检测到[此处原文缺失相关信息]，以及以单核细胞浸润为特征的肉芽肿性病变。大体和组织学检查是诊断包虫病和囊尾蚴病的宝贵工具，提供了条理清晰的基线数据，以增强我们对人畜共患中绦期幼虫负担的理解。
