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采用早期非负重保守治疗的股骨内侧髁软骨下不全骨折。

Subchondral insufficiency fracture of the medial femoral condyle treated conservatively with early non-weightbearing.

作者信息

Maris Alexandros, Al-Khudairi Rashed, Maslaris Alexander, Vasiliadis Angelo V

机构信息

Department of Trauma and Orthopaedics, Royal Free Hospital NHS Trust, London NW3 2QG, United Kingdom.

Department for Health, University of Bath, Bath BA2 7AY, United Kingdom.

出版信息

Radiol Case Rep. 2024 Jul 18;19(10):4158-4162. doi: 10.1016/j.radcr.2024.06.069. eCollection 2024 Oct.

DOI:10.1016/j.radcr.2024.06.069
PMID:39101013
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11293509/
Abstract

Spontaneous osteonecrosis of the knee (SONK) is a poorly understood but debilitating disease, that is a common cause of unilateral acute knee pain and swelling. The term "SONK" has been replaced by the term "subchondral insufficiency fracture" in the latest pathology and imaging literature. Few studies investigated the pathogenesis of SONK by examining the histological changes of the tissues. Very recently, the development of SONK was associated with a meniscal root tear. In terms of the preferred imaging, plain radiographs can confirm the diagnosis in late stages; however, magnetic resonance imaging (MRI) scan is often required. Regarding the treatment, conservative management is usually the treatment of choice in early stages, including a period of non-weightbearing or the use of medications, such as nonsteroidal anti-inflammatory drug (NSAIDS) or bisphosphonates. However, when SONK progresses, often a surgical intervention is required, such as knee replacement, but also minimally invasive techniques, such as arthroscopic intervention, have been described. We present a case of early SONK and discuss the possible pathogenesis of SONK, the clinical presentation, the radiological findings, and we focus on the importance of early diagnosis and early off-load period that is required to prevent further progression of the disease.

摘要

膝关节自发性骨坏死(SONK)是一种了解较少但使人衰弱的疾病,是单侧急性膝关节疼痛和肿胀的常见原因。在最新的病理学和影像学文献中,“SONK”一词已被“软骨下不全骨折”所取代。很少有研究通过检查组织的组织学变化来探究SONK的发病机制。最近,SONK的发展与半月板根部撕裂有关。在首选影像学方面,X线平片可在晚期确诊;然而,通常需要进行磁共振成像(MRI)扫描。在治疗方面,早期通常选择保守治疗,包括一段时间的不负重或使用药物,如非甾体抗炎药(NSAIDs)或双膦酸盐。然而,当SONK进展时,通常需要手术干预,如膝关节置换,但也有描述采用微创技术,如关节镜干预。我们报告一例早期SONK病例,并讨论SONK可能的发病机制、临床表现、影像学表现,同时着重强调早期诊断以及为防止疾病进一步进展所需的早期减负期的重要性。

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2
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本文引用的文献

1
Transient spontaneous osteonecrosis of the knee (SONK) shortly after SARS-CoV-2 infection: A report of 2 cases.感染 SARS-CoV-2 后不久出现的膝关节一过性特发性骨坏死(SONK):2 例报告。
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Biological Effects of High Tibial Osteotomy on Spontaneous Osteonecrosis of the Knee.胫骨高位截骨术对自发性膝关节骨坏死的生物学效应。
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Medicine (Baltimore). 2022 Jul 29;101(30):e29585. doi: 10.1097/MD.0000000000029585.
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Potential Utility of SPECT/CT for Early Detection of Spontaneous Osteonecrosis of the Knee.SPECT/CT 对早期检测自发性膝关节骨坏死的潜在应用价值。
Clin Nucl Med. 2022 Nov 1;47(11):e704-e705. doi: 10.1097/RLU.0000000000004312. Epub 2022 Jun 11.
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Medial meniscus extrusion as a predictor for a poor prognosis in patients with spontaneous osteonecrosis of the knee.内侧半月板挤出作为膝关节自发性骨坏死患者预后不良的预测指标。
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Bisphosphonate for spontaneous osteonecrosis of the knee: A protocol for systematic review and meta-analysis of randomized controlled trials.双膦酸盐治疗膝关节自发性骨坏死:一项随机对照试验的系统评价与荟萃分析方案
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Treatment of spontaneous osteonecrosis of the knee by daily teriparatide: A report of 3 cases.每日使用特立帕肽治疗膝关节自发性骨坏死:3例报告
Medicine (Baltimore). 2020 Jan;99(5):e18989. doi: 10.1097/MD.0000000000018989.
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Injury of the Meniscus Root.半月板根部损伤。
Clin Sports Med. 2020 Jan;39(1):57-68. doi: 10.1016/j.csm.2019.08.009.
9
Spontaneous Osteonecrosis of the Knee.膝关节自发性骨坏死。
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10
Traumatic knee injury: correlation of radiographic effusion size with the presence of internal derangement on magnetic resonance imaging.创伤性膝关节损伤:X线片上积液大小与磁共振成像显示的内部紊乱之间的相关性
Emerg Radiol. 2018 Oct;25(5):479-487. doi: 10.1007/s10140-018-1605-z. Epub 2018 May 8.