Maris Alexandros, Al-Khudairi Rashed, Maslaris Alexander, Vasiliadis Angelo V
Department of Trauma and Orthopaedics, Royal Free Hospital NHS Trust, London NW3 2QG, United Kingdom.
Department for Health, University of Bath, Bath BA2 7AY, United Kingdom.
Radiol Case Rep. 2024 Jul 18;19(10):4158-4162. doi: 10.1016/j.radcr.2024.06.069. eCollection 2024 Oct.
Spontaneous osteonecrosis of the knee (SONK) is a poorly understood but debilitating disease, that is a common cause of unilateral acute knee pain and swelling. The term "SONK" has been replaced by the term "subchondral insufficiency fracture" in the latest pathology and imaging literature. Few studies investigated the pathogenesis of SONK by examining the histological changes of the tissues. Very recently, the development of SONK was associated with a meniscal root tear. In terms of the preferred imaging, plain radiographs can confirm the diagnosis in late stages; however, magnetic resonance imaging (MRI) scan is often required. Regarding the treatment, conservative management is usually the treatment of choice in early stages, including a period of non-weightbearing or the use of medications, such as nonsteroidal anti-inflammatory drug (NSAIDS) or bisphosphonates. However, when SONK progresses, often a surgical intervention is required, such as knee replacement, but also minimally invasive techniques, such as arthroscopic intervention, have been described. We present a case of early SONK and discuss the possible pathogenesis of SONK, the clinical presentation, the radiological findings, and we focus on the importance of early diagnosis and early off-load period that is required to prevent further progression of the disease.
膝关节自发性骨坏死(SONK)是一种了解较少但使人衰弱的疾病,是单侧急性膝关节疼痛和肿胀的常见原因。在最新的病理学和影像学文献中,“SONK”一词已被“软骨下不全骨折”所取代。很少有研究通过检查组织的组织学变化来探究SONK的发病机制。最近,SONK的发展与半月板根部撕裂有关。在首选影像学方面,X线平片可在晚期确诊;然而,通常需要进行磁共振成像(MRI)扫描。在治疗方面,早期通常选择保守治疗,包括一段时间的不负重或使用药物,如非甾体抗炎药(NSAIDs)或双膦酸盐。然而,当SONK进展时,通常需要手术干预,如膝关节置换,但也有描述采用微创技术,如关节镜干预。我们报告一例早期SONK病例,并讨论SONK可能的发病机制、临床表现、影像学表现,同时着重强调早期诊断以及为防止疾病进一步进展所需的早期减负期的重要性。