Stoltz J F
Biomed Pharmacother. 1985;39(6):272-81.
When attempting to apply rheological concepts to the problem of the circulation of blood, researches have often come up against the difficulties inherent in the fluid's specific properties and in the characteristics of blood flow. The concepts that have been fully proven in conventional fluid mechanics have often been applied too hastily to hemodynamics, without even ascertaining the validity of the original hypotheses. The following factors must be taken into account: the specific nature of the fluid (a concentrated cell suspension with complex rheological characteristic such as membrane viscoelasticity, large deformations and liable to undergo high interactions); the characteristics of the blood vessels deformability; the type of flow (essentially non-stationary).
在试图将流变学概念应用于血液循环问题时,研究人员常常遇到该流体特定性质以及血流特性所固有的困难。在传统流体力学中已得到充分证明的概念,常常被过于草率地应用于血液动力学,甚至都没有确定原始假设的有效性。必须考虑以下因素:流体的特殊性质(一种具有复杂流变特性的浓缩细胞悬浮液,如膜粘弹性、大变形且易于发生强烈相互作用);血管可变形性的特点;血流类型(本质上是非定常的)。