Stoltz J F
Biomed Pharmacother. 1985;39(6):282-92.
Whole blood behaves like a deformable colloidal particle suspension in a macromolecular medium. Pathological variations in the rheological properties of blood and the clinical symptoms they produce form the "hyperviscosity syndromes". The term "hyperviscosity" was originally used for characterising the plasma hyperviscosity observed during macroglobulinemia and it is only recently that the chapter covering hyperviscosity syndromes has been enlarged to describe the syndromes as a state in which the increased blood viscosity and increase in flow resistance must be considered as the result of the rheological behaviour of blood taken as a whole (plasma and blood cells). The etiology of hyperviscosity syndromes can be: an increase in total plasma protein levels, or the appearance of a monoclonal protein, the increase in the number of blood cells, the increase in the erythrocyte's internal viscosity, the changes in the erythrocyte's viscoelastic properties, the excessive aggregating tendency of the erythrocytes and perhaps that of the platelets.
全血在大分子介质中表现得像一种可变形的胶体颗粒悬浮液。血液流变学特性的病理变化及其产生的临床症状形成了“高黏滞血症”。术语“高黏滞度”最初用于描述巨球蛋白血症期间观察到的血浆高黏滞度，直到最近，涵盖高黏滞血症的章节才得以扩充，将这些综合征描述为一种状态，即血液黏度增加和血流阻力增加必须被视为整个血液（血浆和血细胞）流变学行为的结果。高黏滞血症的病因可能是：血浆总蛋白水平升高、单克隆蛋白的出现、血细胞数量增加、红细胞内黏度增加、红细胞黏弹性特性的变化、红细胞以及可能还有血小板过度的聚集倾向。
