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类圆线虫病致心脏瓣膜赘生物和双心室心力衰竭。

Valvular Endocarditis and Biventricular Heart Failure in the Setting of Tropheryma whipplei Disease.

机构信息

Department of Cardiovascular Surgery, Mayo Clinic, Rochester, Minnesota.

Department of Internal Medicine, Division of Infectious Diseases, Mayo Clinic, Rochester, Minnesota.

出版信息

Tex Heart Inst J. 2024 Aug 5;51(2). doi: 10.14503/THIJ-23-8336.

DOI:10.14503/THIJ-23-8336
PMID:39101327
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11299065/
Abstract

Whipple disease is a rare systemic illness associated with weight loss, diarrhea, and arthralgia. Asymptomatic carriage is common, but the disease can be complicated by cardiac involvement and may result in culture-negative endocarditis. Cardiac manifestations of the disease can lead to death. This report presents the case of a 66-year-old man with Whipple disease and biventricular heart failure with cardiogenic shock. Medical therapy followed by successful replacement of the aortic and mitral valves resulted in substantial improvement.

摘要

惠普尔病是一种罕见的全身性疾病，与体重减轻、腹泻和关节痛有关。无症状携带很常见，但该病可并发心脏受累，并可能导致培养阴性的心内膜炎。该病的心脏表现可导致死亡。本报告介绍了一例 66 岁男性惠普尔病合并双心室心力衰竭伴心源性休克的病例。经药物治疗和成功置换主动脉瓣和二尖瓣后，病情得到了显著改善。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5156/11299065/d7682312856f/i1526-6702-51-2-e238336-f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5156/11299065/ed88b4fd3112/i1526-6702-51-2-e238336-f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5156/11299065/d7682312856f/i1526-6702-51-2-e238336-f02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5156/11299065/ed88b4fd3112/i1526-6702-51-2-e238336-f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5156/11299065/d7682312856f/i1526-6702-51-2-e238336-f02.jpg

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Valvular Endocarditis and Biventricular Heart Failure in the Setting of Tropheryma whipplei Disease.类圆线虫病致心脏瓣膜赘生物和双心室心力衰竭。
Tex Heart Inst J. 2024 Aug 5;51(2). doi: 10.14503/THIJ-23-8336.
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本文引用的文献

1
Targeting transforming growth factor-β receptors in pulmonary hypertension.靶向肺动脉高压中的转化生长因子-β受体。
Eur Respir J. 2021 Feb 4;57(2). doi: 10.1183/13993003.02341-2020. Print 2021 Feb.
2
Whipple's endocarditis: a case report of a blood culture-negative endocarditis.惠普尔心内膜炎：一例血培养阴性的心内膜炎病例报告。
Eur Heart J Case Rep. 2019 Dec;3(4):1-6. doi: 10.1093/ehjcr/ytz222. Epub 2019 Dec 17.
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Tropheryma whipplei infection and Whipple's disease. tropheryma whipplei 感染和惠特利氏病。
Lancet Infect Dis. 2016 Mar;16(3):e13-22. doi: 10.1016/S1473-3099(15)00537-X. Epub 2016 Feb 6.
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Tropheryma whipplei Endocarditis: A Two-patient Case Series.惠利氏泰勒菌心内膜炎：两例病例系列。
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Tropheryma whipplei endocarditis without gastrointestinal involvement.无胃肠道受累的惠普尔嗜组织菌心内膜炎
Interact Cardiovasc Thorac Surg. 2012 Jul;15(1):161-3. doi: 10.1093/icvts/ivs116. Epub 2012 Apr 11.
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High frequency of Tropheryma whipplei in culture-negative endocarditis.培养阴性心内膜炎中帚虫属的高频率。
J Clin Microbiol. 2012 Feb;50(2):216-22. doi: 10.1128/JCM.05531-11. Epub 2011 Nov 30.
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Persistent reduction of complement receptor 3 alpha-chain expressing mononuclear blood cells and transient inhibitory serum factors in Whipple's disease.
Clin Immunol Immunopathol. 1994 Aug;72(2):217-26. doi: 10.1006/clin.1994.1134.
8
Severe pulmonary hypertension in a patient with Whipple's disease.惠普尔病患者的重度肺动脉高压。
Am J Med. 1985 Aug;79(2):263-7. doi: 10.1016/0002-9343(85)90020-8.