Hautzentrum Köln (Cologne Dermatology), Köln, Germany; Faculty of Health, University Witten-Herdecke, Witten, Germany.
Private Office, Bern, Switzerland.
Acta Derm Venereol. 2024 Aug 5;104:adv40601. doi: 10.2340/actadv.v104.40601.
Keratinocyte-derived skin cancers comprise basal cell carcinoma, squamous cell carcinoma, its precursor actinic keratosis, and Bowen's disease. Historically, this group of neoplasms has been subsumed under the term non-melanoma skin cancer. However, the term non-melanoma skin cancer can be misleading and lacks precision. Therefore, more precise and reasonable terminology, valuing the relevance of keratinocyte-derived cancer, appears pertinent to meet its clinical and scientific significance. A group of experienced dermato-oncologists initiated a consensus approach to promote the use of the term "keratinocyte cancer" instead of "non-melanoma skin cancer" when referring to carcinomas and their precursors that are derived from keratinocytes. The vote among members of the consensus group indicated unanimous agreement on the consistent use of the term "keratinocyte cancer" instead of "non-melanoma skin cancer". International delegates also voted in favour of the revised terminology. The more precise and, by means of etiopathogenesis, correct term "keratinocyte cancer" should be consistently used for malignancies originated from keratinocytes. This is expected to have a positive impact on patient-physician communication and gives better justice to this important group of keratinocyte-derived cancers.
角质细胞源性皮肤癌包括基底细胞癌、鳞状细胞癌、其前体光化性角化病和 Bowen 病。历史上,这组肿瘤被归入非黑素瘤皮肤癌的范畴。然而,“非黑素瘤皮肤癌”这一术语可能具有误导性且不够精确。因此,为了更准确地描述其临床和科学意义,采用更精确且合理的术语来强调角质细胞源性癌症的相关性似乎更为恰当。一组经验丰富的皮肤肿瘤学家发起了一项共识方法,提倡在提到来源于角质细胞的癌及其前体时,使用“角质细胞癌”而非“非黑素瘤皮肤癌”。共识小组成员的投票结果表明,一致同意一致使用“角质细胞癌”而非“非黑素瘤皮肤癌”这一术语。国际代表也投票赞成修订后的术语。源于角质细胞的恶性肿瘤应使用更精确、更具病因学意义的术语“角质细胞癌”。这有望对医患沟通产生积极影响,并使这一重要的角质细胞源性癌症群体得到更公正的对待。