The Key Lab of Health Chemistry & Molecular Diagnosis of Suzhou, College of Chemistry, Chemical Engineering & Materials Science, Soochow University, Suzhou 215123, P.R. China.
Shanghai Animal Disease Control Center, Shanghai 201103, P.R. China.
Analyst. 2024 Sep 9;149(18):4623-4632. doi: 10.1039/d4an00760c.
The "antenna effect" is one of the most important energy transfer modes in lanthanide light-emitting polymers. In this study, novel luminescent nanostructured coordination polymers (Eu-PCP) were synthesized in one step using Eu as the central metal ion and 5,10,15,20-tetrakis (4-carboxyphenyl) porphyrin (TCPP) as the organic ligand. The unique "antenna effect" observed between Eu and TCPP leads to a substantial improvement in the electrochemiluminescence (ECL) emission efficiency. Eu-PCP exhibits good cathodic ECL characteristics. Additionally, Au@SnS nanosheets exhibit favorable electrical conductivity, biocompatibility, and a significant specific surface area. This makes them a suitable choice as substrate materials for the modification of electrode surfaces and capturing antigens. Being well known, the development of sensitive and rapid methods to detect chloramphenicol is essential for food safety. Based on this, we report a novel competitive electrochemiluminescence immunoassay to achieve ultra-sensitive and highly specific detection of chloramphenicol. The linear range was 0.0002-500 ng mL and the detection limit was 0.09 pg mL. Apart from that, the experimental results proved that it provided a new analytical tool for the detection of antibiotic residues in food safety.
“天线效应”是镧系元素发光聚合物中最重要的能量转移模式之一。在这项研究中，我们使用 Eu 作为中心金属离子，5,10,15,20-四(4-羧基苯基)卟啉(TCPP)作为有机配体，一步法合成了新型发光纳米结构配位聚合物(Eu-PCP)。Eu 和 TCPP 之间观察到的独特“天线效应”导致电致化学发光(ECL)发射效率的大幅提高。Eu-PCP 表现出良好的阴极 ECL 特性。此外，Au@SnS 纳米片具有良好的导电性、生物相容性和较大的比表面积。这使得它们成为修饰电极表面和捕获抗原的理想基底材料。众所周知，开发灵敏、快速的氯霉素检测方法对于食品安全至关重要。基于此，我们报道了一种新型的竞争性电化学发光免疫分析方法，用于实现对氯霉素的超灵敏和高特异性检测。线性范围为 0.0002-500ng mL，检测限为 0.09pg mL。此外，实验结果证明，它为食品安全中抗生素残留的检测提供了一种新的分析工具。
