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髋关节镜与物理治疗治疗 40 岁以上症状性髋臼唇撕裂:一项随机对照试验的 24 个月结果。

Hip Arthroscopy Versus Physical Therapy for the Treatment of Symptomatic Acetabular Labral Tears in Patients Older Than 40 Years: 24-Month Results From a Randomized Controlled Trial.

机构信息

Department of Orthopaedic Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.

Department of Orthopaedic Surgery, University of Nebraska, Omaha, Nebraska, USA.

出版信息

Am J Sports Med. 2024 Aug;52(10):2574-2585. doi: 10.1177/03635465241263595. Epub 2024 Aug 5.

Abstract

BACKGROUND

The indications for hip arthroscopy in patients aged ≥40 years remain controversial, as observational studies have suggested that advanced age portends poor functional outcomes, poor durability of improvement, and high rates of conversion to total hip arthroplasty.

PURPOSE

To compare hip arthroscopy versus nonoperative management for symptomatic labral tears in patients aged ≥40 years with limited radiographic osteoarthritis.

STUDY DESIGN

Randomized controlled trial; Level of evidence, 1.

METHODS

This single-surgeon, parallel randomized controlled trial included patients aged ≥40 years with limited osteoarthritis (Tönnis grades 0-2) who were randomized 1:1 to arthroscopic surgery with postoperative physical therapy (SPT) or physical therapy alone (PTA). Patients who received PTA and achieved unsatisfactory improvement were permitted to cross over to SPT after completing ≥14 weeks of physical therapy (CO). The primary outcomes were the International Hip Outcome Tool-33 score and modified Harris Hip Score at 24 months after surgery, and secondary outcomes included other patient-reported outcome measures and the visual analog scale for pain. The primary analysis was performed on an intention-to-treat basis using linear mixed-effects models. Sensitivity analyses included modified as-treated and treatment-failure analyses.

RESULTS

A total of 97 patients were included, with 52 (53.6%) patients in the SPT group and 45 (46.4%) patients in the PTA group. Of the patients who underwent PTA, 32 (71.1%) patients crossed over to arthroscopy at a mean of 5.10 months (SD, 3.3 months) after physical therapy initiation. In both intention-to-treat and modified as-treated analyses, the SPT group displayed superior mean patient-reported outcome measure and pain scores across the study period for nearly all metrics relative to the PTA group. In the treatment-failure analysis, the SPT and CO groups showed greater improvement across all metrics compared with PTA; however, post hoc analyses revealed no significant differences in improvement between the SPT and CO groups. No significant differences were observed between groups in rates of total hip arthroplasty conversion.

CONCLUSION

In patients ≥40 years of age with limited osteoarthritis, hip arthroscopy with postoperative physical therapy led to better outcomes than PTA at a 24-month follow-up. However, additional preoperative physical therapy did not compromise surgical outcomes and allowed some patients to avoid surgery. When surgery is indicated, age ≥40 years should not be considered an independent contraindication to arthroscopic acetabular labral repair.

REGISTRATION

NCT03909178 (ClinicalTrials.gov identifier).

摘要

背景

对于年龄≥40 岁的髋关节患者,髋关节镜检查的适应证仍存在争议,因为观察性研究表明,高龄预示着功能结局较差、改善效果持续时间短以及髋关节置换术转换率高。

目的

比较髋关节镜检查与非手术治疗对有限放射学骨关节炎的≥40 岁症状性盂唇撕裂患者的疗效。

研究设计

随机对照试验;证据水平,1 级。

方法

这是一项由单外科医生进行的平行随机对照试验,纳入了年龄≥40 岁、有限的骨关节炎(Tönnis 分级 0-2 级)的患者,按照 1:1 比例随机分为关节镜手术联合术后物理治疗(SPT)或单纯物理治疗(PTA)组。接受 PTA 且改善不满意的患者,在完成至少 14 周的物理治疗(CO)后,允许交叉至 SPT。主要结局是手术 24 个月后的国际髋关节结果工具-33 评分和改良 Harris 髋关节评分,次要结局包括其他患者报告的结局指标和疼痛视觉模拟评分。主要分析采用意向性治疗的线性混合效应模型进行。敏感性分析包括改良后处理分析和治疗失败分析。

结果

共纳入 97 例患者,其中 SPT 组 52 例(53.6%),PTA 组 45 例(46.4%)。接受 PTA 的患者中,32 例(71.1%)患者在物理治疗开始后平均 5.10 个月(标准差,3.3 个月)时交叉至关节镜。在意向性治疗和改良后处理分析中,与 PTA 组相比,SPT 组在研究期间几乎所有指标的患者报告结局测量和疼痛评分均显示出更好的均值。在治疗失败分析中,与 PTA 组相比,SPT 和 CO 组在所有指标上的改善均更大;然而,事后分析显示 SPT 和 CO 组之间的改善无显著差异。各组间全髋关节置换术转化率无显著差异。

结论

在年龄≥40 岁、有局限性骨关节炎的患者中,与单纯物理治疗相比,术后物理治疗的髋关节镜检查在 24 个月的随访中可获得更好的结果。然而,额外的术前物理治疗并不会影响手术效果,且可以让一些患者避免手术。当需要手术时,年龄≥40 岁不应被视为关节镜髋臼盂唇修复的独立禁忌证。

注册

NCT03909178(ClinicalTrials.gov 标识符)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bb5/11428710/730e89e6051b/10.1177_03635465241263595-fig1.jpg

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