Department of Clinical Pharmacy, College of Pharmacy, Shaqra University, Shaqra, 11961, Saudi Arabia.
Department of Clinical Pharmacy, National Cancer Institute, Cairo University, Fom El Khalig Square, Kasr Al-Aini Street, Cairo, 11796, Egypt.
Arch Dermatol Res. 2024 Aug 5;316(8):502. doi: 10.1007/s00403-024-03230-7.
The meta-analysis sought to evaluate and compare the effect of obesity on surgical site wound problems in subjects after primary ovarian cancer surgery. The results found by this meta-analysis were analyzed, and then odds ratio (OR) and mean difference (MD), at 95% confidence intervals (CIs), were calculated. These models might be dichotomous or contentious, random, or fixed effect models. The current meta-analysis included nine exams from 2009 to 2023, including 4362 females with primary ovarian cancer surgeries. Obesity had a significantly higher risk of surgical site wound infections (OR, 2.90; 95% CI, 2.27-3.69, p < 0.001), and wound problems (OR, 4.14; 95% CI, 1.83-9.34, p < 0.001) compared to non-obesity in females with primary ovarian cancer surgeries. It was revealed, by examining the data, that obesity was associated with significantly higher incidence of surgical site wound infections, and wound problems compared to non-obesity in females with primary ovarian cancer surgeries. However, attention should be given to the values because some of the comparisons included a small number of chosen studies,.
本荟萃分析旨在评估和比较肥胖对原发性卵巢癌手术后患者手术部位伤口问题的影响。对本荟萃分析的结果进行了分析，然后计算了 95%置信区间 (CI) 的优势比 (OR) 和均数差 (MD)。这些模型可能是二项式或有争议的，随机的或固定效应模型。本荟萃分析纳入了 2009 年至 2023 年的 9 项研究，共包括 4362 例原发性卵巢癌手术的女性。肥胖与原发性卵巢癌手术后女性的手术部位伤口感染（OR，2.90；95%CI，2.27-3.69，p<0.001）和伤口问题（OR，4.14；95%CI，1.83-9.34，p<0.001）的风险显著升高有关。通过检查数据发现，与非肥胖相比，肥胖与原发性卵巢癌手术后女性的手术部位伤口感染和伤口问题发生率显著升高有关。然而，应该注意到这些比较中的一些包含了少数选择的研究，因此数值可能存在偏差。
