• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

经皮冠状动脉介入治疗(PCI)和急性冠脉综合征(ACS) 1 个月双抗血小板治疗(DAPT)后,替格瑞洛单药治疗 11 个月可减少出血,而不增加 MACCE。

After PCI and 1 mo of DAPT for ACS, ticagrelor alone vs. continued DAPT for 11 mo reduced bleeding without increasing MACCE.

机构信息

University of Toronto, Toronto, Ontario, Canada (C.C.).

St. Michael's Hospital and University of Toronto, Toronto, Ontario, Canada (A.T.Y.).

出版信息

Ann Intern Med. 2024 Aug;177(8):JC86. doi: 10.7326/ANNALS-24-00968-JC. Epub 2024 Aug 6.

DOI:10.7326/ANNALS-24-00968-JC
PMID:39102721
Abstract

Ge Z, Kan J, Gao X, et al; ULTIMATE-DAPT investigators. Lancet. 2024;403:1866-1878. 38599220.

摘要

葛支棱、阚继坤、高翔、ULTIMATE-DAPT 研究者. 柳叶刀. 2024;403:1866-1878. 38599220.

相似文献

1
After PCI and 1 mo of DAPT for ACS, ticagrelor alone vs. continued DAPT for 11 mo reduced bleeding without increasing MACCE.经皮冠状动脉介入治疗(PCI)和急性冠脉综合征(ACS) 1 个月双抗血小板治疗(DAPT)后,替格瑞洛单药治疗 11 个月可减少出血,而不增加 MACCE。
Ann Intern Med. 2024 Aug;177(8):JC86. doi: 10.7326/ANNALS-24-00968-JC. Epub 2024 Aug 6.
2
Ticagrelor alone versus ticagrelor plus aspirin from month 1 to month 12 after percutaneous coronary intervention in patients with acute coronary syndromes (ULTIMATE-DAPT): a randomised, placebo-controlled, double-blind clinical trial.替格瑞洛单用或替格瑞洛加阿司匹林用于急性冠脉综合征患者经皮冠状动脉介入治疗后 1 至 12 个月(ULTIMATE-DAPT):一项随机、安慰剂对照、双盲临床试验。
Lancet. 2024 May 11;403(10439):1866-1878. doi: 10.1016/S0140-6736(24)00473-2. Epub 2024 Apr 7.
3
Comparison of one-month versus twelve-month dual antiplatelet therapy after implantation of drug-eluting stents guided by either intravascular ultrasound or angiography in patients with acute coronary syndrome: rationale and design of prospective, multicenter, randomized, controlled IVUS-ACS and ULTIMATE-DAPT trial.比较血管内超声或血管造影指导下急性冠脉综合征患者药物洗脱支架植入术后 1 个月与 12 个月双联抗血小板治疗:前瞻性、多中心、随机、对照 IVUS-ACS 和 ULTIMATE-DAPT 试验的原理和设计。
Am Heart J. 2021 Jun;236:49-58. doi: 10.1016/j.ahj.2021.02.014. Epub 2021 Feb 20.
4
De-escalation to ticagrelor monotherapy versus 12 months of dual antiplatelet therapy in patients with and without acute coronary syndromes: a systematic review and individual patient-level meta-analysis of randomised trials.在有和没有急性冠脉综合征的患者中,从双联抗血小板治疗降级为替格瑞洛单药治疗与继续双联抗血小板治疗 12 个月:一项随机试验的系统评价和个体患者水平荟萃分析。
Lancet. 2024 Sep 7;404(10456):937-948. doi: 10.1016/S0140-6736(24)01616-7. Epub 2024 Aug 31.
5
De-escalating Dual Antiplatelet Therapy to Ticagrelor Monotherapy in Acute Coronary Syndrome : A Systematic Review and Individual Patient Data Meta-analysis of Randomized Clinical Trials.急性冠状动脉综合征中双联抗血小板治疗降级为替格瑞洛单药治疗:一项随机临床试验的系统评价和个体患者数据荟萃分析
Ann Intern Med. 2025 Apr;178(4):533-542. doi: 10.7326/ANNALS-24-03102. Epub 2025 Feb 18.
6
Efficacy and safety of ticagrelor monotherapy following a brief DAPT vs. prolonged 12-month DAPT in ACS patients post-PCI: a meta-analysis of RCTs.替格瑞洛单药治疗与 PCI 后 ACS 患者短程 DAPT(<1 个月)与长程 12 个月 DAPT 的疗效和安全性:RCT 的荟萃分析。
Eur J Clin Pharmacol. 2024 Dec;80(12):1871-1882. doi: 10.1007/s00228-024-03747-w. Epub 2024 Sep 12.
7
After stent implantation for ACS, ticagrelor monotherapy after <1 mo of DAPT vs. 12 mo of DAPT improved 1-y net clinical benefit.经 ACS 支架植入术后,替格瑞洛单药治疗(DAPT 时间<1 个月)与 12 个月 DAPT 相比,改善了 1 年净临床获益。
Ann Intern Med. 2024 Jun;177(6):JC64. doi: 10.7326/ANNALS-24-00207-JC. Epub 2024 Jun 4.
8
Short-Term Dual Antiplatelet Therapy After Drug-Eluting Stenting in Patients With Acute Coronary Syndromes: A Systematic Review and Network Meta-Analysis.急性冠状动脉综合征患者药物洗脱支架置入术后的短期双联抗血小板治疗:一项系统评价和网状Meta分析
JAMA Cardiol. 2024 Dec 1;9(12):1094-1105. doi: 10.1001/jamacardio.2024.3216.
9
De-escalation of dual antiplatelet therapy for patients with acute coronary syndrome after percutaneous coronary intervention: a systematic review and network meta-analysis.经皮冠状动脉介入治疗后急性冠状动脉综合征患者双联抗血小板治疗的降阶梯治疗:一项系统评价和网状Meta分析
BMJ Evid Based Med. 2024 May 22;29(3):171-186. doi: 10.1136/bmjebm-2023-112476.
10
Ticagrelor monotherapy after ≤ 1-month DAPT vs continued DAPT in patients with acute coronary syndrome treated with percutaneous coronary intervention: A systematic review and meta-analysis of randomized controlled trials.替格瑞洛单药治疗在接受经皮冠状动脉介入治疗的急性冠状动脉综合征患者中与持续 DAPT 相比在≤1 个月后的疗效:随机对照试验的系统评价和荟萃分析。
Curr Probl Cardiol. 2024 Dec;49(12):102868. doi: 10.1016/j.cpcardiol.2024.102868. Epub 2024 Sep 26.