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高出生体重与 4-5 岁儿童龋齿的关系:一项出生队列研究。

Association between high birth weight and dental caries at 4-5 years of age: a birth-cohort study.

机构信息

Department of Preventive Dentistry, Shanghai Stomatological Hospital & School of Stomatology, Fudan University, Shanghai, China.

Shanghai Key Laboratory of Craniomaxillofacial Development and Diseases, Fudan University, Shanghai, China.

出版信息

BMC Oral Health. 2024 Aug 5;24(1):896. doi: 10.1186/s12903-024-04651-6.

Abstract

OBJECTIVE

Early childhood caries has become a globally crucial oral health problem over the decades. Most studies have discussed the association between low birth weight and early childhood caries; however, studies focusing on high birth weight have been relatively limited. This study aimed to assess the impact of high birth weight on the incidence and severity of dental caries in 4-5-year-old children.

SUBJECTS AND METHODS

Study subjects included 491 children from a birth cohort study at 4-5 years of age. Data on dental caries, prenatal and perinatal factors, and socio-demographic determinants were recorded. Logistic regression models adjusted for potential confounders were performed to analyze the data. Two-sided P-value < 0.05 was considered statistically significant.

RESULTS

Of the 491 children, the prevalence of dental caries was 48.7%. High birth weight (≥ 4,000 g) was significantly associated with increased incidence of dental caries (OR, 2.000; CI 95% 1.062-3.765), and the relatively enhanced risk OR was further increased in subjects experiencing caries (dmft ≥ 3) (OR, 2.437; CI 95% 1.306-4.549) compared with the normal birth weight (2,500-3,999 g).

CONCLUSIONS

High birth weight is a risk factor for early childhood caries. Particular attention should be paid to children with birth weight more than or equal to 4,000 g.

摘要

目的

在过去几十年中,幼儿龋齿已成为全球范围内一个至关重要的口腔健康问题。大多数研究都讨论了低出生体重与幼儿龋齿之间的关系;然而,关注高出生体重的研究相对较少。本研究旨在评估高出生体重对 4-5 岁儿童龋齿发生率和严重程度的影响。

受试者和方法

研究对象包括来自出生队列研究的 491 名 4-5 岁儿童。记录了龋齿、产前和围产期因素以及社会人口决定因素的数据。对数据进行了调整潜在混杂因素的逻辑回归模型分析。双侧 P 值 < 0.05 被认为具有统计学意义。

结果

在 491 名儿童中,龋齿的患病率为 48.7%。高出生体重(≥ 4,000 克)与龋齿发生率增加显著相关(OR,2.000;95%CI 1.062-3.765),并且在患有龋齿(dmft≥3)的受试者中,相对增强的风险 OR 进一步增加(OR,2.437;95%CI 1.306-4.549)与正常出生体重(2,500-3,999 克)相比。

结论

高出生体重是幼儿龋齿的一个危险因素。应特别关注出生体重等于或大于 4,000 克的儿童。

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