Department of Dermatology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
From the The State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau, China.
Clin Nucl Med. 2024 Nov 1;49(11):1036-1038. doi: 10.1097/RLU.0000000000005402. Epub 2024 Aug 5.
A 29-year-old man with Ewing sarcoma in the right ankle underwent 68 Ga-DOTA-IBA PET/CT and 18 F-FDG PET/CT, both of which showed high radiotracer activity for the primary tumor. Interestingly, bone metastases were detected early using 68 Ga-DOTA-IBA PET/CT for the sixth thoracic vertebrae and with 18 F-FDG PET/CT for the bilateral humerus. Higher uptake of 68 Ga-DOTA-IBA was found in both primary and metastatic sites of Ewing sarcoma. 177 Lu-DOTA-IBA may be one of the possible therapies for metastatic or recurrent Ewing sarcoma.
一位 29 岁男性，右侧踝关节患有尤因肉瘤，进行了 68Ga-DOTA-IBA PET/CT 和 18F-FDG PET/CT 检查，这两项检查均显示原发性肿瘤的放射性示踪剂活性很高。有趣的是，使用 68Ga-DOTA-IBA PET/CT 较早地检测到了第六胸椎的骨转移，而使用 18F-FDG PET/CT 检测到了双侧肱骨的骨转移。在尤因肉瘤的原发性和转移性部位均发现了更高的 68Ga-DOTA-IBA 摄取。177Lu-DOTA-IBA 可能是治疗转移性或复发性尤因肉瘤的一种可能方法。
