Kharkevich D D, Polevaia E B, Derevnina N A, Sablikova Iu A, Savinov A Iu
Eksp Onkol. 1985;7(6):69-73.
The simplified micromodification of the leukocyte adhesion inhibition (LAI) test has shown that the LAI tests both for lymphocytes and for leukocytes may be equally used as additional methods of diagnostics of the early stages of breast cancer. The detailed study of the kinetics and cellular mechanisms of the method has shown that the LAI reaction belongs to the earliest reactions of T-cellular immunity and is mediated by T-cell lymphokine. The study of sensitivity and specificity of the method revealed that the suggested micromodification of the LAI test may be used in experimental and clinical research for the study of the subpopulation of T-cells-producers of the LAI factor as well as for monitoring of the T-cell immunity in the cancer patients during treatment.
白细胞黏附抑制（LAI）试验的简化微量改良法表明，淋巴细胞和白细胞的LAI试验均可同样用作乳腺癌早期诊断的辅助方法。对该方法的动力学和细胞机制的详细研究表明，LAI反应属于T细胞免疫的最早反应，由T细胞淋巴因子介导。对该方法的敏感性和特异性的研究表明，所建议的LAI试验微量改良法可用于实验和临床研究，以研究LAI因子产生细胞的T细胞亚群，以及监测癌症患者治疗期间的T细胞免疫。
