Greenlee Kendra J, Padilla Dianna K
Department of Biological Sciences, North Dakota State University, Fargo, ND 58108 USA.
Department of Ecology and Evolution, Stony Brook University, Stony Brook, NY 11794-5245 USA.
Integr Comp Biol. 2024 Aug 5. doi: 10.1093/icb/icae131.
Throughout their lives, organisms must integrate and maintain stability across complex developmental, morphological, and physiological systems, all while responding to changing internal and external environments. Determining the mechanisms underlying organismal responses to environmental change and development is a major challenge for biology. This is particularly important in the face of the rapidly changing global climate, increasing human populations, and habitat destruction. In January 2024, we organized a symposium to highlight some current efforts to use modeling to understand organismal responses to short- and long-term changes in their internal and external environments. Our goal was to facilitate collaboration and communication between modelers and organismal biologists, which is one of the major aims of the Organismal Systems-type Modeling Research Coordination Network, OSyM. Accompanying this introduction are a series of papers that are aimed to enhance research and education in linking organismal biology and modeling and contribute to building a new community of scientists to tackle important questions using this approach.
在整个生命过程中，生物体必须整合并维持复杂的发育、形态和生理系统的稳定性，同时还要应对不断变化的内部和外部环境。确定生物体对环境变化和发育反应的潜在机制是生物学面临的一项重大挑战。面对全球气候迅速变化、人口不断增加以及栖息地遭到破坏的情况，这一点尤为重要。2024年1月，我们组织了一次研讨会，以突出当前一些利用建模来理解生物体对其内部和外部环境短期和长期变化的反应的努力。我们的目标是促进建模人员与生物体生物学家之间的合作与交流，这是生物体系统类型建模研究协调网络（OSyM）的主要目标之一。随此引言一同刊发的还有一系列论文，旨在加强将生物体生物学与建模相联系的研究与教育，并有助于建立一个新的科学家群体，以利用这种方法解决重要问题。
