Wang Mengting, Li Yinshuai, Pan Tiejun, Jia Nan
Ningbo Key Laboratory of Agricultural Germplasm Resources Mining and Environmental Regulation, College of Science and Technology, Ningbo University, Cixi, China.
School of Design, Shanghai Jiao Tong University, Shanghai, China.
Heliyon. 2024 Jul 10;10(14):e34462. doi: 10.1016/j.heliyon.2024.e34462. eCollection 2024 Jul 30.
Plant-derived natural compounds are significant resources for the discovery of potential anticancer drugs. While research in the plant-based anticancer field has surged in recent years, systematic bibliometric analyses covering a longer period and containing up-to-date publications remain scarce. Here, we conducted a bibliometric analysis of literature on the anticancer properties of plant natural compounds over the past three decades, leveraging the bibliometric framework and open-access platform, KNIME. Our findings showed that the number of plant anticancer-related publications underwent an accelerating growth from 1992 to 2023. The country and institution analyses revealed that countries with traditional medical systems contributed a large portion of publications in the plant anticancer field, such as India, China, and South Korea. This study also highlighted the top ten eminent researchers and publications, assisting researchers in identifying pivotal literature. The primary publications were domains of chemistry and biology-related fields, such as Pharmacology & Pharmacy, Plant Sciences, and Biochemistry & Molecular Biology. Additionally, we noted that flavonoids have been focal plant compounds in anticancer, with strong anticancer potential. Our study provides new insights into the progress and trends in the plant anticancer field and will assist researchers in grasping the future research direction.
植物源天然化合物是发现潜在抗癌药物的重要资源。尽管近年来基于植物的抗癌领域研究激增，但涵盖更长时间段且包含最新出版物的系统文献计量分析仍然稀缺。在此，我们利用文献计量框架和开放获取平台KNIME，对过去三十年关于植物天然化合物抗癌特性的文献进行了文献计量分析。我们的研究结果表明，1992年至2023年期间，与植物抗癌相关的出版物数量呈加速增长。国家和机构分析显示，拥有传统医学体系的国家在植物抗癌领域贡献了很大一部分出版物，如印度、中国和韩国。本研究还突出了十大杰出研究人员和出版物，帮助研究人员识别关键文献。主要出版物集中在化学和生物学相关领域，如药理学与制药学、植物科学以及生物化学与分子生物学。此外，我们注意到黄酮类化合物一直是抗癌领域的重点植物化合物，具有很强的抗癌潜力。我们的研究为植物抗癌领域的进展和趋势提供了新的见解，并将帮助研究人员把握未来的研究方向。
