Fischer Patrick, Mahfoud Felix, Böhm Michael, Ukena Christian
Klinik für Innere Medizin III, Kardiologie, Angiologie und Internistische Intensivmedizin, Universitätsklinikum des Saarlandes, Saarland University, Kirrberger Str. 100, Geb. 41.1, 66421 Homburg (Saar), Germany.
Klinik für Kardiologie, Universitätsspital Basel, Basel, Switzerland.
Eur Heart J Case Rep. 2024 Jul 18;8(8):ytae334. doi: 10.1093/ehjcr/ytae334. eCollection 2024 Aug.
Patients with atrial fibrillation (AF) are at increased risk for thromboembolic events including stroke. The primary source for thromboembolism in these patients is thrombus formation in the left atrial appendage (LAA). Depending on the individual thromboembolic risk, long-term anticoagulation is recommended. In certain patients, however, long-term anticoagulation is contraindicated, and interventional closure of the LAA (LAAC) represents an alternative approach to lower the thromboembolic risk and avoid oral anticoagulation.
An 83-year-old male underwent LAAC at our centre in November 2022. Prior to the procedure, a thrombus in the left atrium (LA) or LAA was excluded by transoesophageal echocardiography (TOE), and the anatomy of the LAA was assessed as eligible for LAAC with no evidence of anatomical irregularities. After contrast medium injection, angiography revealed an atypical anatomic variant of the LAA with a substantially long, elephant trunk-like course.
We present a previously not described unique anatomic variant of the LAA: the elephant trunk morphology. Left atrial appendage anatomy is very heterogeneous, and detailed knowledge of LAA morphology is important for endovascular LAA procedures as well as for predicting the risk of thromboembolic events. Despite thorough pre-procedural imaging, anatomic variants may remain obscured.
心房颤动(AF)患者发生包括中风在内的血栓栓塞事件的风险增加。这些患者血栓栓塞的主要来源是左心耳(LAA)内血栓形成。根据个体血栓栓塞风险,建议进行长期抗凝治疗。然而,在某些患者中,长期抗凝治疗是禁忌的,LAA介入封堵术(LAAC)是降低血栓栓塞风险并避免口服抗凝治疗的另一种方法。
一名83岁男性于2022年11月在我们中心接受了LAAC。术前,经食管超声心动图(TOE)排除了左心房(LA)或LAA内的血栓,且LAA解剖结构经评估适合LAAC,无解剖结构异常的证据。注射造影剂后,血管造影显示LAA存在一种非典型解剖变异,其走行呈长的象鼻样。
我们展示了一种此前未描述过的LAA独特解剖变异:象鼻形态。左心耳解剖结构非常多样,详细了解LAA形态对于血管内LAA手术以及预测血栓栓塞事件风险都很重要。尽管术前进行了全面的影像学检查,但解剖变异可能仍难以发现。