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食管粪石伴可口可乐和胰酶(胰脂肪酶)导致的严重气道梗阻:一例贲门失弛缓症患者的综合病例报告

Severe Airway Obstruction Caused by Esophageal Bezoar with Coca-Cola and Creon (Pancrelipase) in a Patient with Underlying Achalasia: A Comprehensive Case Report.

作者信息

Urlapu Kinnera Sahithi, Mantri Nikhitha, Patel Harish, Lajara Hallal Priscilla, Chilimuri Sridhar, Diaz-Fuentes Gilda

机构信息

Division of Pulmonary and Critical Care Department of Medicine Bronx Care Health System Affiliated with Icahn School of Medicine at Mount Sinai, New York, Bronx, USA.

Division of Gastroenterology Department of Medicine Bronx Care Health System Affiliated with Icahn School of Medicine at Mount Sinai, New York, Bronx, USA.

出版信息

Case Rep Gastrointest Med. 2024 Jul 27;2024:2081040. doi: 10.1155/2024/2081040. eCollection 2024.

Abstract

INTRODUCTION

The occurrence of acute respiratory failure as a result of esophageal bezoars is a rare phenomenon. We present a patient who failed initial endoscopic intervention. Successful resolution was achieved through a novel approach involving a combination of Creon and Coca-Cola. Subsequently, the patient was diagnosed with achalasia, a condition that potentially contributed to the formation of the esophageal bezoar. . An 82-year-old man presented with respiratory distress, necessitating endotracheal intubation for airway protection. A chest computed tomogram (CT) showed pneumonia and a distended esophagus compressing the trachea, raising the possibility of an esophageal food bolus. Endoscopy revealed a severely dilated esophagus containing a significant amount of food and a phytobezoar in the lower esophagus. He failed various endoscopic techniques to remove the obstruction. Given the patient's poor surgical candidacy, he was started in a thrice-daily regimen of Creon dissolved in 165 mL of Coca-Cola, over a 4-day period. A subsequent endoscopy revealed no discernible evidence of food or bezoar. The patient was weaned from mechanical ventilation. A high-resolution esophageal manometry identified type 1 achalasia.

CONCLUSION

Esophageal food impaction leading to respiratory failure is rare. Endoscopy remains the mainstay approach. Surgical interventions carry significant risks. This case emphasizes the potential for noninvasive management in patients with esophageal bezoars and also underscores the significance of contemplating esophageal pathologies when addressing cases of respiratory failure. The use of Coca-Cola and Creon emerges as a safe, effective, and cost-efficient treatment, providing a feasible option when endoscopy proves unsuccessful before considering more aggressive interventions.

摘要

引言

食管粪石导致急性呼吸衰竭是一种罕见现象。我们报告一名患者,其最初的内镜干预未成功。通过一种涉及胰酶肠溶胶囊(Creon)和可口可乐联合使用的新方法成功解决了问题。随后,该患者被诊断为贲门失弛缓症,这种疾病可能促成了食管粪石的形成。一名82岁男性因呼吸窘迫就诊,需要进行气管插管以保护气道。胸部计算机断层扫描(CT)显示有肺炎以及扩张的食管压迫气管,提示存在食管食物团块的可能性。内镜检查发现食管严重扩张,下食管内有大量食物和一个植物粪石。他尝试了各种内镜技术来清除梗阻,但均未成功。鉴于患者手术耐受性差,开始让他在4天内每日三次服用溶解于165毫升可口可乐中的胰酶肠溶胶囊。随后的内镜检查未发现食物或粪石的明显迹象。患者成功脱机。高分辨率食管测压确定为1型贲门失弛缓症。

结论

食管食物嵌塞导致呼吸衰竭很罕见。内镜检查仍然是主要的治疗方法。手术干预风险很大。该病例强调了食管粪石患者无创治疗的可能性,也突出了在处理呼吸衰竭病例时考虑食管病变的重要性。可口可乐和胰酶肠溶胶囊的联合使用是一种安全、有效且经济高效的治疗方法,在内镜检查失败后,在考虑更积极的干预措施之前提供了一种可行的选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1e88/11300067/2bf537105551/CRIGM2024-2081040.001.jpg

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