• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

肥胖青少年高血压的诊断与管理

Diagnosis and Management of Hypertension in Adolescents with Obesity.

作者信息

Chhabria Shradha M, LeBron Jared, Ronis Sarah D, Batt Courtney E

机构信息

Department of Medicine, Case Western Reserve University School of Medicine, Cleveland, OH USA.

Department of Pediatrics, Case Western Reserve University School of Medicine, Cleveland, OH USA.

出版信息

Curr Cardiovasc Risk Rep. 2024;18(8-9):115-124. doi: 10.1007/s12170-024-00740-x. Epub 2024 Jul 30.

DOI:10.1007/s12170-024-00740-x
PMID:39105085
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11297811/
Abstract

PURPOSE OF REVIEW

Hypertension (HTN) and obesity are increasing in prevalence and severity in adolescents and have significant implications for long term morbidity and mortality. This review focuses on the diagnosis and management of HTN in adolescents with obesity with an emphasis on co-management of the two conditions.

RECENT FINDINGS

Recent studies affirm the increasing prevalence of abnormal blood pressures and diagnoses of HTN associated with increased adiposity. Current guidelines recommend routine screening with proper technique for HTN in patients with obesity. Additionally, obesity and HTN related co-occurring medical conditions should be evaluated as there is frequently a bidirectional impact on risk and outcomes. Importantly, advances in adolescent obesity management have subsequently led to positive implications for the management of obesity-related comorbidities such as HTN. The co-management of obesity and HTN is an emerging strategy for treatment and prevention of additional morbidity and mortality as patients progress to adulthood.

SUMMARY

In adolescent patients with obesity, prompt recognition and appropriate diagnosis of HTN as well as related co-occurring conditions are necessary first steps in management. Co-management of obesity and HTN is likely to lead to improved outcomes. While lifestyle interventions serve as the foundation to this management, adjunctive and emerging therapies should be considered to adequately treat both conditions.

摘要

综述目的

高血压(HTN)和肥胖症在青少年中的患病率和严重程度正在上升,对长期发病率和死亡率有重大影响。本综述重点关注肥胖青少年高血压的诊断和管理,强调对这两种情况的联合管理。

最新发现

最近的研究证实,与肥胖增加相关的血压异常和高血压诊断的患病率正在上升。当前指南建议对肥胖患者进行高血压常规筛查,并采用适当技术。此外,应评估肥胖和高血压相关的并发疾病,因为它们对风险和结局往往有双向影响。重要的是,青少年肥胖管理的进展随后对肥胖相关合并症(如高血压)的管理产生了积极影响。肥胖和高血压的联合管理是一种新兴策略,可在患者步入成年期时预防更多的发病率和死亡率。

总结

在肥胖的青少年患者中,及时识别和正确诊断高血压以及相关的并发疾病是管理的首要必要步骤。肥胖和高血压的联合管理可能会改善结局。虽然生活方式干预是这种管理的基础,但应考虑辅助和新兴疗法以充分治疗这两种情况。

相似文献

1
Diagnosis and Management of Hypertension in Adolescents with Obesity.肥胖青少年高血压的诊断与管理
Curr Cardiovasc Risk Rep. 2024;18(8-9):115-124. doi: 10.1007/s12170-024-00740-x. Epub 2024 Jul 30.
2
Diagnosis, Evaluation, and Management of High Blood Pressure in Children and Adolescents.儿童和青少年高血压的诊断、评估和管理。
Pediatrics. 2018 Sep;142(3). doi: 10.1542/peds.2018-2096. Epub 2018 Aug 20.
3
Comparison of Trends in Blood Pressure and the Prevalence of Obesity Among Korean and American Adolescents: A 12-Years Cross-sectional Study.韩国和美国青少年血压趋势与肥胖患病率的比较:一项为期12年的横断面研究。
J Prev Med Public Health. 2020 Jan;53(1):45-55. doi: 10.3961/jpmph.19.198. Epub 2019 Nov 20.
4
[Association between the blood pressure status and nutritional status among Chinese students aged 7-18 years in 2014: based on the national blood pressure reference for Chinese children and adolescents].2014年中国7-18岁学生血压状况与营养状况的关联:基于中国儿童青少年血压参考标准
Beijing Da Xue Xue Bao Yi Xue Ban. 2018 Jun 18;50(3):422-428.
5
[PRIMARY HYPERTENSION IN CHILDREN AND ADOLESCENTS].[儿童和青少年原发性高血压]
Harefuah. 2021 Apr;160(4):260-265.
6
Hypertension in children: new trends and challenges.儿童高血压:新趋势和新挑战。
Clin Sci (Lond). 2010 May 14;119(4):151-61. doi: 10.1042/CS20090544.
7
Implications of the 2017 AAP Clinical Practice Guidelines for Management of Hypertension in Children and Adolescents: a Review.2017 年美国儿科学会临床实践指南对儿童和青少年高血压管理的影响:综述。
Curr Hypertens Rep. 2019 Apr 5;21(5):35. doi: 10.1007/s11906-019-0943-x.
8
Evaluation and Management of Stage 2 Hypertension in Pediatric Patients.儿童 2 期高血压的评估和管理。
Curr Hypertens Rep. 2018 Jul 6;20(9):73. doi: 10.1007/s11906-018-0873-z.
9
10
Prevalence of hypertension and its associations with body composition across Chinese and American children and adolescents.中国和美国儿童青少年高血压的患病率及其与身体成分的关系。
World J Pediatr. 2024 Apr;20(4):392-403. doi: 10.1007/s12519-023-00740-8. Epub 2023 Jul 13.

引用本文的文献

1
Cardiovascular Assessments in Children and Adolescents With Hypertension.高血压儿童和青少年的心血管评估
Rev Cardiovasc Med. 2025 Aug 25;26(8):39498. doi: 10.31083/RCM39498. eCollection 2025 Aug.

本文引用的文献

1
What is the pipeline for future medications for obesity?未来治疗肥胖症的药物研发流程是怎样的?
Int J Obes (Lond). 2025 Mar;49(3):433-451. doi: 10.1038/s41366-024-01473-y. Epub 2024 Feb 1.
2
The effectiveness of physical activity interventions on blood pressure in children and adolescents: A systematic review and network meta-analysis.身体活动干预对儿童和青少年血压的影响:系统评价和网络荟萃分析。
J Sport Health Sci. 2024 Sep;13(5):699-708. doi: 10.1016/j.jshs.2024.01.004. Epub 2024 Jan 19.
3
Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes.司美格鲁肽在肥胖但无糖尿病患者中的心血管结局。
N Engl J Med. 2023 Dec 14;389(24):2221-2232. doi: 10.1056/NEJMoa2307563. Epub 2023 Nov 11.
4
Phentermine/Topiramate for the Treatment of Adolescent Obesity.苯丁胺/托吡酯治疗青少年肥胖症
NEJM Evid. 2022 Jun;1(6). doi: 10.1056/evidoa2200014. Epub 2022 Apr 30.
5
Clinical Practice Guideline for the Evaluation and Treatment of Children and Adolescents With Obesity.儿童和青少年肥胖评估与治疗临床实践指南
Pediatrics. 2023 Feb 1;151(2). doi: 10.1542/peds.2022-060640.
6
Appraisal of Clinical Care Practices for Child Obesity Treatment. Part II: Comorbidities.临床儿童肥胖治疗护理实践评价。第二部分:合并症。
Pediatrics. 2023 Feb 1;151(2). doi: 10.1542/peds.2022-060643.
7
Narrative update of clinical trials with antihypertensive drugs in children and adolescents.儿童和青少年使用抗高血压药物的临床试验的叙述性更新。
Front Cardiovasc Med. 2022 Nov 21;9:1042190. doi: 10.3389/fcvm.2022.1042190. eCollection 2022.
8
Once-Weekly Semaglutide in Adolescents with Obesity.每周一次司美格鲁肽治疗肥胖青少年。
N Engl J Med. 2022 Dec 15;387(24):2245-2257. doi: 10.1056/NEJMoa2208601. Epub 2022 Nov 2.
9
Medical treatment of weight loss in children and adolescents with obesity.儿童和青少年肥胖的减肥治疗。
Pharmacol Res. 2022 Nov;185:106471. doi: 10.1016/j.phrs.2022.106471. Epub 2022 Sep 26.
10
Hypertension is prevalent in non-alcoholic fatty liver disease and increases all-cause and cardiovascular mortality.高血压在非酒精性脂肪性肝病中普遍存在,并增加全因死亡率和心血管疾病死亡率。
Front Cardiovasc Med. 2022 Aug 8;9:942753. doi: 10.3389/fcvm.2022.942753. eCollection 2022.