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吲哚菁绿在妇科良性手术中的创新应用:提高安全性与精准度。

Innovative ICG Application in Benign Gynaecological Surgery: Enhancing Safety and Precision.

作者信息

Menezes Summer Deah, Rao Tanushree

机构信息

Obstetrics and Gynaecology Department Liverpool Hospital, Locked Bag 7103 Liverpool 2170, Sydney, NSW, Australia.

University of New South Wales South Western Sydney Clinical School Liverpool Hospital, Level 2, Clinical Building, Locked Bag 7103 Liverpool 2170, Sydney, NSW, Australia.

出版信息

Case Rep Obstet Gynecol. 2024 Jul 26;2024:1642315. doi: 10.1155/2024/1642315. eCollection 2024.

DOI:10.1155/2024/1642315
PMID:39105141
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11300066/
Abstract

In the context of increased adoption of minimally invasive surgery for benign gynaecological conditions, this study underscores the paramount importance of patient safety. We explored the efficacy of indocyanine green (ICG), a fluorescent dye, in enhancing the visualisation of critical anatomical structures during complex laparoscopic procedures. Our methods involved the direct administration of ICG into the ureters for precise identification and dissection, as well as an innovative vaginal application to delineate the rectovaginal plane in cases with distorted pelvic anatomy. The study presented two cases: a laparoscopic hysterectomy for a multifibroid uterus and a case of advanced endometriosis with rectal involvement. Results indicated that ICG use significantly improved real-time visualisation of the ureters and the rectovaginal plane, which facilitated the surgeries and reduced the cognitive load on surgeons. There were no intraoperative complications, and the postoperative phase showed positive patient outcomes. In conclusion, the application of ICG in these laparoscopic surgeries proved to be a beneficial adjunct, suggesting its potential for broader application in benign gynaecological surgeries. Future research is warranted to explore additional uses of ICG, with a focus on enhancing patient safety and surgical efficacy.

摘要

在越来越多采用微创手术治疗良性妇科疾病的背景下,本研究强调了患者安全的至关重要性。我们探讨了荧光染料吲哚菁绿(ICG)在复杂腹腔镜手术中增强关键解剖结构可视化方面的功效。我们的方法包括将ICG直接注入输尿管以进行精确识别和解剖,以及一种创新的经阴道应用方法,用于在盆腔解剖结构扭曲的病例中勾勒直肠阴道平面。该研究展示了两个病例:一例为多肌瘤子宫的腹腔镜子宫切除术,另一例为累及直肠的晚期子宫内膜异位症。结果表明,使用ICG显著改善了输尿管和直肠阴道平面的实时可视化,这有助于手术进行并减轻了外科医生的认知负担。术中无并发症发生,术后患者情况良好。总之,ICG在这些腹腔镜手术中的应用被证明是一种有益的辅助手段,表明其在良性妇科手术中具有更广泛应用的潜力。有必要进行未来研究以探索ICG的更多用途,重点是提高患者安全性和手术疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/684d/11300066/584f29a35649/CRIOG2024-1642315.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/684d/11300066/fd85a099e172/CRIOG2024-1642315.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/684d/11300066/716e96792546/CRIOG2024-1642315.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/684d/11300066/54005eb5cfc0/CRIOG2024-1642315.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/684d/11300066/584f29a35649/CRIOG2024-1642315.004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/684d/11300066/fd85a099e172/CRIOG2024-1642315.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/684d/11300066/716e96792546/CRIOG2024-1642315.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/684d/11300066/54005eb5cfc0/CRIOG2024-1642315.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/684d/11300066/584f29a35649/CRIOG2024-1642315.004.jpg

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本文引用的文献

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Use of indocyanine green for ureteric illumination and visualization.
Int J Gynecol Cancer. 2024 Apr 1;34(4):643-644. doi: 10.1136/ijgc-2023-005042.
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Intraoperative Fluorescent Ureter Visualization in Complex Laparoscopic or Robotic-Assisted Gynecologic Surgery.复杂腹腔镜或机器人辅助妇科手术中输尿管的术中荧光可视化
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Surgical management of uterine fibroids.子宫肌瘤的外科治疗。
Curr Opin Obstet Gynecol. 2023 Oct 1;35(5):440-445. doi: 10.1097/GCO.0000000000000903. Epub 2023 Aug 2.
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Fluorescence-guided surgery: comprehensive review.荧光引导手术:全面综述。
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European Association for Endoscopic Surgery (EAES) consensus on Indocyanine Green (ICG) fluorescence-guided surgery.欧洲内镜外科学会(EAES)关于吲哚菁绿(ICG)荧光引导手术的共识。
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Iatrogenic ureteric injury during abdominal or pelvic surgery: a meta-analysis.医源性输尿管损伤在腹部或盆腔手术期间:一项荟萃分析。
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Surgeons' workload assessment during indocyanine-assisted deep endometriosis surgery using the surgery task load index: The impact of the learning curve.使用手术任务负荷指数评估吲哚菁绿辅助深部子宫内膜异位症手术期间外科医生的工作量:学习曲线的影响
Front Surg. 2022 Sep 5;9:982922. doi: 10.3389/fsurg.2022.982922. eCollection 2022.
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Rates of severe complications in patients undergoing colorectal surgery for deep endometriosis-a retrospective multicenter observational study.深部子宫内膜异位症行结直肠手术患者严重并发症的发生率:一项回顾性多中心观察性研究。
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The Use of near Infra-Red Radiation Imaging after Injection of Indocyanine Green (NIR-ICG) during Laparoscopic Treatment of Benign Gynecologic Conditions: Towards Minimalized Surgery. A Systematic Review of Literature.近红外辐射成像在腹腔镜治疗良性妇科疾病中使用吲哚菁绿(NIR-ICG)后:迈向最小化手术。文献系统评价。
Medicina (Kaunas). 2022 Jun 13;58(6):792. doi: 10.3390/medicina58060792.
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J Minim Invasive Gynecol. 2022 May;29(5):586-587. doi: 10.1016/j.jmig.2022.01.018. Epub 2022 Feb 10.