Department of Urology, Faculty of Medicine and Health, Örebro University, 701 85, Örebro, Sweden.
Department of Radiology, Faculty of Medicine and Health, Örebro University, Örebro, Sweden.
Urolithiasis. 2024 Aug 6;52(1):114. doi: 10.1007/s00240-024-01604-0.
Stone size and location are key factors in predicting spontaneous stone passage (SSP), but little attention has been paid to the influence of radiological signs of stone impaction (RSSI). This research aims to determine whether RSSI, alongside stone size, can predict SSP and to evaluate the consistency of ureteral wall thickness (UWT) measurements among observers. In this retrospective study, 160 patients with a single upper or middle ureteral stone on acute non-enhanced computed tomography (NCCT) were analysed. Patient data were collected from medical records. Measurements of RSSI, including UWT, ureteral diameters, and average attenuation above and below the stone, were taken on NCCT by four independent readers blind to the outcomes. The cohort consisted of 70% males with an average age of 51 ± 15. SSP occurred in 61% of patients over 20 weeks. The median stone length was 5.7 mm (IQR: 4.5-7.3) and was significantly shorter in patients who passed their stones at short- (4.6 vs. 7.1, p < 0.001) and long-term (4.8 vs. 7.1, p < 0.001) follow-up. For stone length, the area under the receiver operating characteristic curve (AUC) for predicting SSP was 0.90 (CI 0.84-0.96) and only increased to 0.91 (CI 0.85-0.95) when adding ureteral diameters and UWT. Ureteral attenuation did not predict SSP (AUC < 0.5). Interobserver variability for UWT was moderate, with ± 2.0 mm multi-reader limits of agreement (LOA). The results suggest that RSSI do not enhance the predictive value of stone size for SSP. UWT measurements exhibit moderate reliability with significant interobserver variability.
结石大小和位置是预测结石自行排出(SSP)的关键因素,但很少关注结石嵌顿的放射学征象(RSSI)的影响。本研究旨在确定 RSSI 与结石大小是否可以预测 SSP,并评估观察者之间输尿管壁厚度(UWT)测量的一致性。在这项回顾性研究中,对 160 名在急性非增强计算机断层扫描(NCCT)上有单个上或中输尿管结石的患者进行了分析。患者数据从病历中收集。由四位独立的读者在 NCCT 上进行 RSSI 测量,包括 UWT、输尿管直径以及结石上下的平均衰减,读者对结果不知情。队列由 70%的男性组成,平均年龄为 51±15 岁。20 周内 61%的患者出现 SSP。结石长度的中位数为 5.7mm(IQR:4.5-7.3),在短期(4.6 与 7.1,p<0.001)和长期(4.8 与 7.1,p<0.001)随访中排出结石的患者中明显更短。对于结石长度,预测 SSP 的受试者工作特征曲线(ROC)下面积(AUC)为 0.90(CI 0.84-0.96),仅当加入输尿管直径和 UWT 时,AUC 才增加到 0.91(CI 0.85-0.95)。输尿管衰减不能预测 SSP(AUC<0.5)。UWT 的观察者间变异性为中度,多读者的±2.0mm 一致性限(LOA)。结果表明,RSSI 不会增强结石大小对 SSP 的预测价值。UWT 测量具有中度可靠性,观察者间存在显著的变异性。