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用六种指标评估俄罗斯成年人肥胖的流行率及其与高血压、糖尿病和高胆固醇血症的关联。

Assessing the prevalence of obesity in a Russian adult population by six indices and their associations with hypertension, diabetes mellitus and hypercholesterolaemia.

机构信息

Department of Community Medicine, UiT The Arctic University of Norway, Tromsø, Norway.

International Research Competence Centre, Northern State Medical University, Arkhangelsk, Russia.

出版信息

Int J Circumpolar Health. 2024 Dec;83(1):2386783. doi: 10.1080/22423982.2024.2386783. Epub 2024 Aug 6.

DOI:10.1080/22423982.2024.2386783
PMID:39106414
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11305031/
Abstract

The anthropometric index that best predicts cardiometabolic risk remains inconclusive. This study therefore assessed the prevalence of obesity using six indices and compared their associations with obesity-related cardiometabolic disorders. We determined obesity prevalence according to body mass index, waist circumference, waist-to-hip ratio, waist-to-height ratio (WHtR), body fat percentage and fat mass index (FMI) using data from the Know Your Heart study ( = 4495, 35-69 years). The areas under the receiver operating characteristic curves (AUCs) provided predictive values of each index for detecting the presence of hypertension, hypercholesterolaemia and diabetes. Age-standardised obesity prevalence significantly varied according to anthropometric index: from 17.2% (FMI) to 75.8% (WHtR) among men and from 23.6% (FMI) to 65.0% (WHtR) among women. WHtR had the strongest association with hypertension (AUC = 0.784;  < 0.001) and with a combination of disorders (AUC = 0.779;  < 0.001) in women. In women, WHtR also had the largest AUCs for hypercholesterolaemia, in men - for hypertension, diabetes and a combination of disorders, although not all the differences from other obesity indices were significant. WHtR exhibited the closest association between hypertension and a combination of disorders in women and was non-inferior compared to other indices in men.

摘要

用于预测心血管代谢风险的最佳人体测量学指数仍存在不确定性。因此,本研究评估了使用六种指数衡量肥胖的患病率,并比较了它们与肥胖相关的心血管代谢疾病的相关性。我们根据体重指数、腰围、腰臀比、腰高比(WHtR)、体脂百分比和脂肪质量指数(FMI),利用 Know Your Heart 研究的数据( = 4495,35-69 岁)确定了肥胖的患病率。接受者操作特征曲线下面积(AUC)提供了每个指数检测高血压、高胆固醇血症和糖尿病存在的预测值。经年龄标准化后,肥胖的患病率根据人体测量学指数显著不同:男性从 17.2%(FMI)到 75.8%(WHtR),女性从 23.6%(FMI)到 65.0%(WHtR)。WHtR 与女性高血压(AUC = 0.784; < 0.001)和多种疾病(AUC = 0.779; < 0.001)的相关性最强。在女性中,WHtR 对高胆固醇血症的 AUC 最大,而在男性中,WHtR 对高血压、糖尿病和多种疾病的 AUC 最大,尽管并非所有与其他肥胖指数的差异均有统计学意义。WHtR 与女性高血压和多种疾病之间的相关性最为密切,与男性的其他指数相比具有非劣效性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddbc/11305031/70fb313ee7d6/ZICH_A_2386783_F0003_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddbc/11305031/71eac524d1ad/ZICH_A_2386783_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddbc/11305031/7dcf1a6da386/ZICH_A_2386783_F0002_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddbc/11305031/70fb313ee7d6/ZICH_A_2386783_F0003_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddbc/11305031/71eac524d1ad/ZICH_A_2386783_F0001_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddbc/11305031/7dcf1a6da386/ZICH_A_2386783_F0002_OC.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ddbc/11305031/70fb313ee7d6/ZICH_A_2386783_F0003_OC.jpg

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