Hebei Key Laboratory of Public Health Safety, School of Life Sciences, College of Public Health, Hebei University, Baoding 071002, China.
Hebei Key Laboratory of Public Health Safety, School of Life Sciences, College of Public Health, Hebei University, Baoding 071002, China.
J Chromatogr A. 2024 Sep 13;1732:465209. doi: 10.1016/j.chroma.2024.465209. Epub 2024 Jul 23.
The use of pesticides has increased with the development of agriculture. However, due to the trace content and the matrix's inherent complexity in environmental water, development of rapid and sensitive detection method present significant challenges in the analysis of pesticide residues. The study synthesized magnetic graphene oxide (MGO) by combining superparamagnetic nanoparticles with the easy modification of graphene oxide (GO). Covalent organic frameworks (COFs) were then modified to have a large specific surface area. Finally, magnetic graphene oxide-based covalent organic frameworks, namely MGO-COFs, were obtained with a spherical structure and used as magnetic solid-phase extraction materials, which was successfully used to determine the seven pesticide residues in environmental samples in conjunction with high performance liquid chromatography. The method has a wide linear range for the tested pesticides, with satisfactory correlation coefficients (R ≥ 0.099) and low detection limits (0.3-1.21 μg L). The correlation coefficients for all seven pesticides were high (R ≥ 0.9996). The spiked recoveries, exhibiting a range of 91.3 to 109 %, demonstrated that the developed MGO-COF-MSPE-HPLC-UV method is simple, efficient, and suitable for the analysis and detection of seven pesticide residues in environmental water.
随着农业的发展，农药的使用量增加了。然而，由于环境水中农药残留的痕量含量和基质的固有复杂性，开发快速灵敏的检测方法在分析农药残留方面存在重大挑战。本研究通过将超顺磁性纳米粒子与氧化石墨烯（GO）易于修饰的特点相结合，合成了磁性氧化石墨烯（MGO）。然后对共价有机骨架（COFs）进行修饰，以获得更大的比表面积。最后，得到了基于磁性氧化石墨烯的共价有机骨架，即 MGO-COFs，其具有球形结构，并结合高效液相色谱法成功用于测定环境样品中的七种农药残留。该方法对所测试的农药具有较宽的线性范围，具有令人满意的相关系数（R≥0.99）和较低的检测限（0.3-1.21μg L）。所有七种农药的相关系数均很高（R≥0.9996）。加标回收率在 91.3%至 109%之间，表明所开发的 MGO-COF-MSPE-HPLC-UV 方法简单、高效，适用于环境水中七种农药残留的分析和检测。
