Department of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden; Department of Orthopedics, Södersjukhuset, Stockholm, Sweden.
Knee. 2024 Oct;50:27-32. doi: 10.1016/j.knee.2024.07.015. Epub 2024 Aug 5.
Previous studies have shown the risk of post-traumatic osteoarthritis to be high following tibial plateau fracture surgery. Several investigations have examined the risk of total knee arthroplasty (TKA) following tibial plateau fracture treatment, but the risk of TKA in relation to the general population in Sweden has not previously been explored.
To determine the incidence of TKA following surgical treatment of tibial plateau fractures and compare it with that of an age-matched population in Sweden.
A total of 349 tibial plateau fractures treated with open reduction internal fixation between 2002 and 2010 were identified from local hospital registers using diagnosis and surgical codes. The cohort was cross-matched with the Swedish Knee Arthroplasty Register to determine which patients had been treated with TKA within 10 years of fracture surgery. The incidence of primary TKA in the age-matched population in Sweden was obtained from the National Patient Register for comparison.
Mortality-adjusted prevalence of TKA at 10 years following fracture surgery was 6.7% (relative risk (RR) = 5.5) and peaked during the second postoperative year (RR=19.3). High age was independently associated with increased risk of TKA (P=0.004); no other examined patient factors were significantly associated with TKA.
The overall prevalence of TKA at 10 years following tibial plateau fracture surgery is low at 6.7%, however the risk is many times greater than that of the age-matched population in Sweden. The majority of patients require TKA within a few years of fracture treatment, hence post-traumatic osteoarthritis may arguably have not been the reason for TKA as this would have taken longer to develop.
既往研究表明胫骨平台骨折术后发生创伤后骨关节炎的风险较高。多项研究调查了胫骨平台骨折治疗后全膝关节置换术(TKA)的风险,但瑞典尚未探讨胫骨平台骨折患者与普通人群相比 TKA 的风险。
确定手术治疗胫骨平台骨折后 TKA 的发生率,并与瑞典年龄匹配人群进行比较。
通过诊断和手术代码,从当地医院登记处确定 2002 年至 2010 年期间接受切开复位内固定治疗的 349 例胫骨平台骨折。使用瑞典膝关节置换登记处对该队列进行交叉匹配,以确定哪些患者在骨折手术后 10 年内接受了 TKA 治疗。通过全国患者登记处获得瑞典年龄匹配人群中原发性 TKA 的发生率,以进行比较。
骨折手术后 10 年 TKA 的死亡率校正患病率为 6.7%(相对风险(RR)=5.5),并在术后第二年达到峰值(RR=19.3)。高龄与 TKA 风险增加独立相关(P=0.004);其他检查的患者因素与 TKA 无显著相关性。
胫骨平台骨折手术后 10 年 TKA 的总体患病率为 6.7%,相对较低,但风险是瑞典年龄匹配人群的许多倍。大多数患者在骨折治疗后几年内需要 TKA,因此创伤后骨关节炎可能不是 TKA 的原因,因为这需要更长的时间才能发展。