Animal Health Laboratory, University of Guelph, Guelph, Ontario, Canada.
Department of Pathobiology, University of Guelph, Guelph, Ontario, Canada.
J Vet Diagn Invest. 2024 Nov;36(6):804-808. doi: 10.1177/10406387241265955. Epub 2024 Aug 6.
From 2014-2023, infectious bronchitis virus (IBV) was detected in 6,589 samples from Canada, and partial nucleotide (nt) sequences of the IBV spike protein () gene were determined for 1,678 samples. Based on their gene nt sequence identities and origin, Canadian IBVs could be classified into 4 groups: 1) 50.3% were variant viruses related to strains described in the United States; 2) 45.6% were vaccine-like viruses; 3) 2.1% were Eurasian viruses; 4) 2.0% were Canadian variants. Outbreaks with IBVs related to strains CAL1734/04, 4/91, and DMV/1639/11 were often associated with more severe disease in all chicken commodity groups. With the emergence of numerous IBV strains, the severity of infection and number of affected flocks increased. Outbreaks with various IBV strains overlapped in their emergence, peaked, and regressed, but the introduction of DMV/1639/11 has resulted in a continuous field challenge since its first detection in 2015.
从 2014 年到 2023 年，在加拿大的 6589 个样本中检测到传染性支气管炎病毒（IBV），并对 1678 个样本的 IBV 刺突蛋白（S）基因部分核苷酸（nt）序列进行了测定。根据其 S 基因 nt 序列的同源性和来源，加拿大 IBV 可分为 4 组：1）50.3%为与美国描述的菌株相关的变异株；2）45.6%为疫苗样病毒；3）2.1%为欧亚病毒；4）2.0%为加拿大变异株。与 CAL1734/04、4/91 和 DMV/1639/11 株相关的 IBV 暴发常与所有商品鸡群更严重的疾病有关。随着大量 IBV 株的出现，感染的严重程度和受影响的鸡群数量增加。各种 IBV 株的暴发在出现、高峰和消退方面相互重叠，但自 2015 年首次检测到 DMV/1639/11 以来，它一直持续存在于田间挑战。
