Division of Cancer Control and Population Sciences, National Cancer Institute, National Institutes of Health, U.S. Department of Health and Human Services, Bethesda, MD, USA.
J Natl Cancer Inst Monogr. 2024 Aug 15;2024(66):199-201. doi: 10.1093/jncimonographs/lgae025.
Expanding legal access to medical cannabis across the United States increases availability and use of cannabis products to manage cancer-related symptoms and treatment side effects despite the lack of research-based evidence on its potential benefits and harms. To address knowledge gaps in how cancer patients access and use cannabis, their perceived risks and benefits with its use, and whether cancer patients discuss cannabis use with their healthcare providers during treatment, the National Cancer Institute (NCI) supported 12 NCI-designated comprehensive cancer centers to conduct surveys, which included NCI standardized core questions on cannabis use during treatment, among their cancer patient populations. This overview highlights key results from the articles contained in the monograph, which includes a summary of the results of core questions across all centers and reports from individual or groups of cancer centers on survey results related to the sourcing of cannabis, associated cost, behavioral factors associated with cannabis use (such as smoking, drinking, or using other substances), patient-provider communication on cannabis use during treatment, ethnic variations in patterns, sources, and reasons for cannabis use as well as methodologic concerns related to survey data analysis. The results of these surveys of cannabis use after the diagnosis of cancer lay the groundwork for much-needed research to answer the questions of benefits and harms, including potential interactions with cancer treatments for cancer patients.
在美国扩大医用大麻的合法准入范围,尽管缺乏关于其潜在益处和危害的基于研究的证据,但增加了管理癌症相关症状和治疗副作用的大麻产品的供应和使用。为了了解癌症患者如何获得和使用大麻、他们对使用大麻的潜在风险和益处的看法,以及癌症患者在治疗期间是否与医疗保健提供者讨论大麻的使用情况,美国国家癌症研究所(NCI)支持 12 个 NCI 指定的综合性癌症中心,在其癌症患者群体中进行调查,其中包括 NCI 在治疗期间使用大麻的标准化核心问题。本概述重点介绍了专论中包含的文章的主要结果,其中包括所有中心核心问题结果的总结,以及个别或多个癌症中心关于大麻来源、相关成本、与大麻使用相关的行为因素(如吸烟、饮酒或使用其他物质)、患者与提供者在治疗期间就大麻使用进行沟通、与大麻使用模式、来源和原因有关的种族差异以及与调查数据分析相关的方法学问题的报告。这些癌症诊断后大麻使用调查的结果为急需的研究奠定了基础,以回答益处和危害的问题,包括癌症患者与癌症治疗的潜在相互作用。