Mănescu Măriuca, Grama Alina, Dincă Andreea Ligia, Chinceșan Mihaela
Emergency County Hospital Targu-Mures, Targu Mures, Romania.
George Emil Palade University of Medicine, Pharmacy, Science, and Technology of Targu Mures, Romania.
J Crit Care Med (Targu Mures). 2024 Jul 31;10(3):261-265. doi: 10.2478/jccm-2024-0024. eCollection 2024 Jul.
Although rarely diagnosed in the pediatric population, deep vein thrombosis (DVT) is experiencing a growing incidence, while continuously acquiring different nuances due to the widening range of risk factors and lifestyle changes in children and adolescents.
A 17-year-old female within four weeks after child delivery was admitted to our clinic due to a six-month history of pain in the left hypochondriac region. After a thorough evaluation, the presence of a benign splenic cyst was revealed, which was later surgically removed. Following the intervention, the patient developed secondary thrombocytosis and bloodstream infection which, together with pre-existing risk factors (obesity, compressive effect of a large cyst, the postpartum period, the presence of a central venous catheter, recent surgery, and post-operative mobilization difficulties) led to the occurrence of extensive DVT, despite anticoagulant prophylaxis and therapy with low-molecular-weight heparin.
DVT raises many challenges for the pediatrician, requiring a personalized approach. Although rare, pediatric patients with multiple concomitant high-risk factors should benefit from interdisciplinary care as DVT may not respond to standard therapy in such cases and rapidly become critical. Continual efforts to better understand and treat this condition will contribute to improved outcomes for pediatric patients affected by DVT.
尽管儿童深静脉血栓形成(DVT)的诊断很少见,但由于儿童和青少年的危险因素范围不断扩大以及生活方式的改变,其发病率正在上升,同时不断呈现出不同的细微差别。
一名17岁女性在分娩四周后因左季肋区疼痛六个月而入住我们的诊所。经过全面评估,发现存在良性脾囊肿,随后进行了手术切除。干预后,患者出现继发性血小板增多症和血流感染,再加上先前存在的危险因素(肥胖、大囊肿的压迫作用、产后期、中心静脉导管的存在、近期手术以及术后活动困难),尽管进行了抗凝预防和低分子量肝素治疗,仍导致广泛的DVT发生。
DVT给儿科医生带来了许多挑战,需要个性化的方法。尽管罕见,但具有多种伴随高危因素的儿科患者应受益于跨学科护理,因为在这种情况下DVT可能对标准治疗无反应并迅速变得危急。不断努力更好地理解和治疗这种疾病将有助于改善受DVT影响的儿科患者的预后。