Tandirerung Fistra J, Jamieson Alexandra, Hendrick Elizabeth, Hughes Alun D, Jones Siana
MRC Unit for Lifelong Health and Ageing at UCL, Department of Population Science and Experimental Medicine, Institute for Cardiovascular Science, University College London, London, United Kingdom.
Department of Cardiology and Vascular Medicine, Sardjito Central Public Hospital, Gadjah Mada University, Yogyakarta, Indonesia.
Front Physiol. 2024 Jul 23;15:1429673. doi: 10.3389/fphys.2024.1429673. eCollection 2024.
Near-infrared spectroscopy (NIRS) provides a non-invasive, cost-effective method for assessing skeletal muscle oxidative capacity when combined with a short exercise protocol and arterial occlusions. However, the impact of different exercise protocols and reproducibility of the method in non-athletic adults have not previously been assessed.
Young, non-athletic adults (YA) were invited to perform a short duration, fast frequency contraction (SF) exercise protocol and a long duration slow frequency (LS) contraction protocol, combined with NIRS measurements and arterial occlusions to assess skeletal muscle oxidative capacity. YA and older non-athletic adults (OA; >65 years old) were invited to perform the SF exercise protocol twice to assess the reproducibility of this oxidative capacity measurement.
We included 25 participants (14 male (56%), age range: 18-86 years) in the analyses. There was a strong positive correlation and good agreement between time constants derived following the SF and LS exercise protocols (Lin's concordance correlation coefficient: 0.69, -value < 0.001 mean bias [LoA]: -3.2 [-31.0, 24.4] seconds. There was a strong positive correlation and good agreement between time constants derived from the SF exercise protocol in the YA & OA group (Lin's concordance correlation coefficient: 0.63, -value < 0.001; mean bias [LoA] -6.4 [-34.0, 21.3] seconds).
These data provide evidence to suggest that NIRS is a reliable method for the assessment of skeletal muscle oxidative capacity irrespective of exercise protocol duration or muscle contraction frequency. NIRS-measured oxidative capacity via the SF exercise protocol was reproducible in non-athletic adults with a wide range in age.
近红外光谱（NIRS）与短时间运动方案和动脉闭塞相结合时，为评估骨骼肌氧化能力提供了一种非侵入性、经济高效的方法。然而，此前尚未评估不同运动方案对非运动员成年人该方法的影响及可重复性。
邀请年轻的非运动员成年人（YA）进行短时间、高频率收缩（SF）运动方案和长时间、低频率（LS）收缩方案，并结合NIRS测量和动脉闭塞来评估骨骼肌氧化能力。邀请YA和老年非运动员成年人（OA；年龄>65岁）进行两次SF运动方案，以评估这种氧化能力测量的可重复性。
我们纳入了25名参与者（14名男性（56%），年龄范围：18 - 86岁）进行分析。SF和LS运动方案后得出的时间常数之间存在强正相关和良好一致性（林氏一致性相关系数：0.69，P值<0.001；平均偏差[LoA]：-3.2[-31.0, 24.4]秒）。YA和OA组中SF运动方案得出的时间常数之间存在强正相关和良好一致性（林氏一致性相关系数：0.63，P值<0.001；平均偏差[LoA] -6.4[-34.0, 21.3]秒）。
这些数据提供了证据，表明无论运动方案持续时间或肌肉收缩频率如何，NIRS都是评估骨骼肌氧化能力的可靠方法。通过SF运动方案经NIRS测量的氧化能力在年龄范围广泛的非运动员成年人中具有可重复性。
