Garcia-Sanchez Paula, Romero-Trancón David, Falces-Romero Iker, Navarro Carrera Paula, Ruiz-Carrascoso Guillermo, Carmena David, Casares Jiménez María, Rivero-Juárez Antonio, Moya Laura, Rodón Jaume, Esperón Fernando, Pérez-Hernando Belén, Sánchez-León Rocío, Hurtado-Gallego Jara, Alcolea Sonia, Sainz Talía, Calvo Cristina, Méndez-Echevarría Ana
Pediatric Emergency Department, La Paz University Hospital, Madrid, Spain.
Hospital La Paz Institute for Health Research (IdiPAZ), Madrid, Spain.
Front Vet Sci. 2024 Jul 23;11:1425870. doi: 10.3389/fvets.2024.1425870. eCollection 2024.
Although pets provide several social-emotional benefits for children, the risk of zoonosis must be considered among immunocompromised individuals.
A prospective study was conducted in a tertiary hospital including immunocompromised patients younger than 20 years owning dogs and/or cats. Colonization and/or infection was evaluated by stool studies, bacterial swabs, blood polymerase chain reaction and serological studies in both patients and their pets, to evaluate potential zoonotic transmission occurrence.
We included 74 patients and their 92 pets (63 dogs, 29 cats). Up to 44.6% of the patients and 31.5% of the pets had at least 1 positive result. Up to 18.4% of pets' fecal samples were positive (bacteria, parasites or hepatitis E virus). No helminths were observed despite the high frequency of incorrect intestinal deworming practices. Among children, gastrointestinal microorganisms were found in 37.3% (primarily ). Colonization by was common among pets (8.0%) but not among children (0.0%). No shared colonization between owners and pets was observed, except in one case ( in both patient and pet feces). Among patients, serologies were positive for (14.8%), (3.2%), (19.1%) and hepatitis E (5.6%). Serology was positive for spp. (22.6%) and spp. (6.5%) in dogs and for spp. (14.3%) and spp. (14.3%) in cats.
Exposure to zoonotic agents was detected in both patients and pets; however, shared colonization events were almost nonexistent. In our cohort, dogs and cats do not appear to entail high zoonosis transmission risk for immunocompromised patients.
尽管宠物能为儿童带来诸多社会情感益处，但免疫功能低下者必须考虑人畜共患病的风险。
在一家三级医院对20岁以下养犬和/或养猫的免疫功能低下患者进行了一项前瞻性研究。通过对患者及其宠物进行粪便研究、细菌拭子检查、血液聚合酶链反应和血清学研究，评估定植和/或感染情况，以评估潜在的人畜共患病传播情况。
我们纳入了74名患者及其92只宠物（63只狗，29只猫）。高达44.6%的患者和31.5%的宠物至少有1项阳性结果。高达18.4%的宠物粪便样本呈阳性（细菌、寄生虫或戊型肝炎病毒）。尽管肠道驱虫做法错误的频率很高，但未观察到蠕虫。在儿童中，37.3%发现了胃肠道微生物（主要是 ）。宠物中 定植很常见（8.0%），但儿童中未发现（0.0%）。除1例（患者和宠物粪便中均有 ）外，未观察到主人和宠物之间的共同定植。在患者中， 血清学阳性率为（14.8%）， 为（3.2%）， 为（19.1%），戊型肝炎为（5.6%）。狗的 spp.血清学阳性率为（22.6%）， spp.为（6.5%），猫的 spp.为（14.3%）， spp.为（14.3%）。
在患者和宠物中均检测到接触人畜共患病原体的情况；然而，共同定植事件几乎不存在。在我们的队列中，狗和猫似乎不会给免疫功能低下的患者带来高人畜共患病传播风险。
