Shanghai Institute of Materia Medica, Chinese Academy of Sciences, No. 501 Haike Road, Shanghai, 201203, China.
Future Microbiol. 2024 Aug 12;19(12):1081-1096. doi: 10.2217/fmb-2023-0220. Epub 2024 Aug 7.
() is a 'star strain' that has attracted much attention in recent years. can effectively regulate host metabolism, significantly affect host immune function, and play an important role in balancing host health and disease. As one of the organs most closely related to the gut (the two can communicate through the hepatic portal vein and bile duct system), liver is widely affected by intestinal microorganisms. A growing body of evidence suggests that may alleviate liver-related diseases by improving the intestinal barrier, energy metabolism and regulating inflammation through its protein components and metabolites. This paper systematically reviews the key roles of and its derivatives in maintaining liver health and improving liver disease.
（）是近年来备受关注的“明星菌株”。可以有效调节宿主代谢，显著影响宿主免疫功能，在维持宿主健康和疾病平衡方面发挥着重要作用。作为与肠道关系最密切的器官之一（两者可以通过肝门静脉和胆管系统进行交流），肝脏广泛受到肠道微生物的影响。越来越多的证据表明，通过其蛋白质成分和代谢物改善肠道屏障、能量代谢和调节炎症，可能缓解与肝脏相关的疾病。本文系统综述了（）及其衍生物在维持肝脏健康和改善肝脏疾病方面的关键作用。
