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光生物调节作用在腭裂牙槽嵴裂术后植骨中的临床研究

Clinical Study of Photobiomodulation Effect at Postoperative Clefted Alveolar Ridge Bone Grafting.

作者信息

Guerrini Luísa Belluco, de Freitas Nicole Rosa, de Azevedo-Silva Lucas José, Dos Santos Caroline Chapernate Vieira, Machado Maria Aparecida de Andrade Moreira, de Oliveira Thais Marchini, Almeida Ana Lúcia Pompéia Fraga de

机构信息

Private Dental Practice, Piracicaba.

Hospital for Rehabilitation of Craniofacial Anomalies, University of São Paulo.

出版信息

J Craniofac Surg. 2024 Aug 7. doi: 10.1097/SCS.0000000000010524.

Abstract

This study aimed to evaluate photobiomodulation (PBM) adjunct effect on pain, swelling, and face temperature in individuals with oral cleft submitted to alveolar ridge bone grafting (ABG). The sample consisted of 46 patients with either incomplete or complete unilateral cleft lip and palate aged from 9 to 18 years, both sexes, who underwent ABG with chin donor area. Subjects were randomly divided into 3 groups: (1) Control (C): ABG (n=17); (2) PBM: ABG with PBM (n=14); (3) Simulated photobiomodulation (SPBM): ABG with SPBM (n=15). Aluminum Gallium Arsenide (GaAlAs) infrared laser was used at 808±10 nm and power of 100 mW±20%. GaAlAs infrared laser was applied on 14 points in the subject's face at 4J per point, at 2 times: Immediate postoperative period and 24 hours postoperative. The authors evaluated pain, swelling, and face temperature at 24 hours postoperative; at 7-day postoperative, the authors evaluated pain, medication use, and swelling decreasing perception. No statistically significant difference occurred between groups C, PBM, and SPBM. At 24 hours postoperative, pain values showed statistically significant difference (P=0.04) between group C and SPBM. PBM at the tested parameters did not reduce pain and swelling and did not significantly change face temperature of individuals submitted to ARBG.

摘要

本研究旨在评估光生物调节(PBM)对接受牙槽嵴植骨术(ABG)的腭裂患者疼痛、肿胀及面部温度的辅助作用。样本包括46例年龄在9至18岁之间、患有不完全或完全性单侧唇腭裂的患者,男女皆有,均接受了取自下巴供区的ABG手术。受试者被随机分为3组:(1)对照组(C):接受ABG手术(n = 17);(2)PBM组:接受ABG手术并进行PBM治疗(n = 14);(3)模拟光生物调节(SPBM)组:接受ABG手术并进行SPBM治疗(n = 15)。使用波长为808±10 nm、功率为100 mW±20%的砷化镓铝(GaAlAs)红外激光。将GaAlAs红外激光以每点4J的能量照射受试者面部的14个点,共照射2次:术后即刻及术后24小时。作者在术后24小时评估疼痛、肿胀及面部温度;在术后7天,作者评估疼痛、药物使用情况及肿胀减轻的感知。C组、PBM组和SPBM组之间未出现统计学上的显著差异。在术后24小时,C组和SPBM组之间的疼痛值显示出统计学上的显著差异(P = 0.04)。在所测试参数下,PBM并未减轻接受ARBG手术患者的疼痛和肿胀,也未显著改变其面部温度。

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